在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Guinea pig Mu-type opioid receptor (OPRM1), partial

  • 中文名稱:
    Recombinant Guinea pig Mu-type opioid receptor(OPRM1),partial
  • 貨號(hào):
    CSB-YP016361GU1
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Guinea pig Mu-type opioid receptor(OPRM1),partial
  • 貨號(hào):
    CSB-EP016361GU1
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Guinea pig Mu-type opioid receptor(OPRM1),partial
  • 貨號(hào):
    CSB-EP016361GU1-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Guinea pig Mu-type opioid receptor(OPRM1),partial
  • 貨號(hào):
    CSB-BP016361GU1
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Guinea pig Mu-type opioid receptor(OPRM1),partial
  • 貨號(hào):
    CSB-MP016361GU1
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    OPRM1; Mu-type opioid receptor; M-OR-1; MOR-1; Fragment
  • 種屬:
    Cavia porcellus (Guinea pig)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell type-specific activity is predominantly coupled to pertussis toxin-sensitive G(i) and G(o) G alpha proteins, GNAI1, GNAI2, GNAI3 and GNAO1, and to a lesser extent to pertussis toxin-insensitive G alpha proteins GNAZ and GNA15. They mediate an array of downstream cellular responses, including inhibition of adenylate cyclase activity and both N-type and L-type calcium channels, activation of inward rectifying potassium channels, mitogen-activated protein kinase (MAPK), phospholipase C (PLC), phosphoinositide/protein kinase (PKC), phosphoinositide 3-kinase (PI3K) and regulation of NF-kappa-B. Also couples to adenylate cyclase stimulatory G alpha proteins. The selective temporal coupling to G-proteins and subsequent signaling can be regulated by RGSZ proteins, such as RGS9, RGS17 and RGS4. Phosphorylation by members of the GPRK subfamily of Ser/Thr protein kinases and association with beta-arrestins is involved in short-term receptor desensitization. Beta-arrestins associate with the GPRK-phosphorylated receptor and uncouple it from the G-protein thus terminating signal transduction. The phosphorylated receptor is internalized through endocytosis via clathrin-coated pits which involves beta-arrestins. The activation of the ERK pathway occurs either in a G-protein-dependent or a beta-arrestin-dependent manner and is regulated by agonist-specific receptor phosphorylation. Acts as a class A G-protein coupled receptor (GPCR) which dissociates from beta-arrestin at or near the plasma membrane and undergoes rapid recycling. Receptor down-regulation pathways are varying with the agonist and occur dependent or independent of G-protein coupling. Endogenous ligands induce rapid desensitization, endocytosis and recycling. Heterooligomerization with other GPCRs can modulate agonist binding, signaling and trafficking properties. Involved in neurogenesis.
  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein. Cell projection, axon. Perikaryon. Cell projection, dendrite. Endosome.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 欧美阿v高清资源在线| 亚洲另类欧美综合在线| 亚洲无日韩码精品| 日韩99在线 | 中文| 日日摸日日碰人妻无码| 欧美老肥妇做爰bbww| 少妇无码一区二区三区| 精品亚洲一区二区三区在线播放| 夜精品一区二区无码a片| 亚洲精品久久久久中文字幕二区 | 亚洲男人的天堂在线播放| 日躁夜躁狠狠躁2001| 精品视频国产狼友视频| 天堂中文在线8最新版地址| 亚洲午夜久久久影院伊人| 欧美一区二区三区视频在线观看| 18禁男女污污污午夜网站免费暖暖| 手机真实国产乱子伦对白视频| 强奷乱码中文字幕熟女一| 人妻无码一区二区三区av| 国产亚洲精选美女久久久久| 亚洲中文字幕无码乱线| 无码国产69精品久久久久孕妇| 亚洲人成在线观看网站不卡| 国产在线观看高清视频黄网| 成人午夜福利视频| 国产精品久久久久久爽爽爽 | 中国少妇初尝黑人巨高清| 清纯小美女主播流白浆| 午夜福利理论片在线观看播放| 精品国产成人一区二区三区 | 又粗又硬又大又爽免费视频播放| 国产精品videossex久久发布 | 一本一道波多野结衣av黑人| 女人爽到喷水的视频大全| 精品无码成人网站久久久久久| 国产亚洲精品久久久久的角色| 丰满少妇弄高潮了www| 国产揉捏爆乳巨胸挤奶视频| 欧美日韩国产中文高清视频| 中文字幕 制服 亚洲 另类|