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  4. Recombinant Gloydius brevicaudus Zinc metalloproteinase/disintegrin

Recombinant Gloydius brevicaudus Zinc metalloproteinase/disintegrin

  • 中文名稱：
    Recombinant Gloydius brevicaudus Zinc metalloproteinase/disintegrin
  • 貨號：
    CSB-YP835467GGO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Gloydius brevicaudus Zinc metalloproteinase/disintegrin
  • 貨號：
    CSB-EP835467GGO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Gloydius brevicaudus Zinc metalloproteinase/disintegrin
  • 貨號：
    CSB-EP835467GGO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Gloydius brevicaudus Zinc metalloproteinase/disintegrin
  • 貨號：
    CSB-BP835467GGO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Gloydius brevicaudus Zinc metalloproteinase/disintegrin
  • 貨號：
    CSB-MP835467GGO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom metalloproteinase brevilysin L4; SVMP; Snake venom metalloproteinase hxl-1; EC 3.4.24.-); Disintegrin salmosin-1; Platelet aggregation inhibitor); Disintegrin salmosin-1 minor component; Disintegrin brevicaudin-2b)]; Fragment
  • 種屬：
    Gloydius brevicaudus (Korean slamosa snake) (Agkistrodon halys brevicaudus)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    27-228
  • 氨基酸序列
    TPAH QRYIELVIVA DHGMFTKYNG DSDKIREWVR QMVNTVDEIY SYMYIDVALA GLEIWSNEDL INVQPAAPHT LDSFGKWRER DLLHRIHHDN AMLLTAIDFD GPTIGLAYVG TMCKPKGSTG VVQDHSTINL RVAVTMAHEI GHNLGIHHDT GSCSCGGYSC IMSPVISHEP SKYFSDCSYT QCWDFIMNQK PQCILNKP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    metalloproteinase that impairs hemostasis in the envenomed animal.; inhibits GPIIb/GPIIIa (ITGA2B/ITGB3) binding to immobilized fibrinogen with an IC(50) of 2.2 nM and ADP-induced platelet aggregation with an IC(50) of 131 nM, respectively. Inhibits angiogenesis. By binding to vitronectin receptor (alpha-V/beta-3 (ITGAV/ITGB3)), also induces apoptosis of endothelial cells by blocking their attachment to extracellular matrix proteins.; inhibits platelet aggregation induced by ADP (IC(50) is 30 nM), collagen (IC(50) is 500 nM), thrombin and epinephrin (IC(50) is 160 nM).
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Venom metalloproteinase (M12B) family, P-II subfamily, P-IIa sub-subfamily
  • 組織特異性：
    Expressed by the venom gland.


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