在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Escherichia coli Chaperone surA (surA)

  • 中文名稱:
    大腸桿菌surA重組蛋白
  • 貨號:
    CSB-BP359693ENV
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大腸桿菌surA重組蛋白
  • 貨號:
    CSB-EP359693ENV-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大腸桿菌surA重組蛋白
  • 貨號:
    CSB-MP359693ENV
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    surA
  • Uniprot No.:
  • 別名:
    surA; b0053; JW0052; Chaperone SurA; Peptidyl-prolyl cis-trans isomerase SurA; PPIase SurA; EC 5.2.1.8; Rotamase SurA; Survival protein A
  • 種屬:
    Escherichia coli (strain K12)
  • 蛋白長度:
    Full length of Chaperone SurA HAMAP-Rule MF_01183 domain
  • 表達區域:
    21-428aa
  • 氨基酸序列
    APQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESLAQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Chaperone involved in the correct folding and assembly of outer membrane proteins, such as OmpA, OmpF and LamB. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. Essential for the survival of E.coli in stationary phase. Required for pilus biogenesis.
  • 基因功能參考文獻:
    1. SurA cycles between distinct conformational and functional states during the bacterial outer membrane assembly process. PMID: 26728192
    2. These findings suggest an autoinhibitory mechanism for regulation of SurA chaperone activity through interdomain interactions involving a proline isomerase domain. PMID: 23943764
    3. mutational studies on SurA to identify residues that are critical for function were conducted; formation of disulfide bond in mutants has no observable detrimental effect on protein activity, indicating SurA does not undergo large-scale conformational change while performing its function PMID: 23275244
    4. The results indicate that FimD usher follows the SurA-BamB pathway for its assembly. PMID: 21784935
    5. Unfolded protein molecules initially form a highly dynamic complex with the chaperone domain of SlyD, and they are then transferred to the prolyl isomerase domain. PMID: 21147124
    6. The biological importance of SurA was further substantiated by the finding that SurA also affects pathogenicity, being required for full virulence of uropathogenic Escherichia coli. PMID: 20447864
    7. Data found that the periplasmic disulfide isomerase DsbC cooperates with SurA and the thiol oxidase DsbA in the folding of the essential beta-barrel protein LptD. PMID: 20615876
    8. SurA was shown to be involved in the assembly of pili PMID: 16267292
    9. SurA therefore asserts a recognition preference for aromatic amino acids in a variety of sequence configurations by adopting alternative tertiary and quaternary structures to bind peptides in different conformations PMID: 17825319
    10. SurA is the primary chaperone responsible for the periplasmic transit of the bulk mass of OMPs to the YaeT complex. PMID: 17908933
    11. data support role for SurA in assembly of LptD & suggest that LptD is a true SurA substrate; based on results, we propose a revised model in which only a subset of outer membrane (OM) proteins depends on SurA for proper folding & insertion in the OM PMID: 19343722

    顯示更多

    收起更多

  • 亞細胞定位:
    Periplasm. Note=Is capable of associating with the outer membrane.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲精品美女久久久久99| 免费人成视频网站在线下载| 中文在线中文a| 日本护士毛茸茸xx| 九九热久久只有精品2| 久久不见久久见免费影院国语| 日产精品久久久久久久| 精品国产三级a∨在线| 无码成人aaaaa毛片| 欧美丰满少妇xxxx性| 亚洲最新版av无码中文字幕| 午夜成人性刺激免费视频| 日韩欧美群交p片內射中文| 亚洲中文字幕无码中字| 久久久精品国产sm调教网站| 精品麻豆一区二区三区乱码| 亚洲爆乳成av人在线蜜芽| 顶级欧美熟妇高潮xxxxx| 国产美女裸体无遮挡免费视频| 亚洲色成人网一二三区| 亚洲人成网站观看在线播放| 麻豆视传媒精品av| 国内精品久久久久久影院8f| 亚洲狠狠婷婷综合久久久久图片| 无码夜色一区二区三区| 免费观看潮喷到高潮中文字幕| 欧美亚洲日本日韩在线| 老头边吃奶边弄进去呻吟| 亚洲成av人片在线观看无码不卡| 在线观看无码不卡av中文| 亚洲精品久久国产精品浴池| 99久久精品费精品国产| 国产黄a三级三级三级| 业余 自由 性别 成熟视频 视频 | 亚洲h在线播放在线观看h| 在线aⅴ亚洲中文字幕| 国产午夜亚洲精品国产成人| 久久人妻精品白浆国产| 俺也来俺也去俺也射| 国产精品黄页免费高清在线观看 | 亚洲日韩一区二区三区|