在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Drosophila melanogaster Voltage-dependent calcium channel type A subunit alpha-1 (cac), partial

  • 中文名稱:
    Recombinant Drosophila melanogaster Voltage-dependent calcium channel type A subunit alpha-1(cac) ,partial
  • 貨號:
    CSB-YP310084DLU
  • 說明書:
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Drosophila melanogaster Voltage-dependent calcium channel type A subunit alpha-1(cac) ,partial
  • 貨號:
    CSB-EP310084DLU
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Drosophila melanogaster Voltage-dependent calcium channel type A subunit alpha-1(cac) ,partial
  • 貨號:
    CSB-EP310084DLU-B
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Drosophila melanogaster Voltage-dependent calcium channel type A subunit alpha-1(cac) ,partial
  • 貨號:
    CSB-BP310084DLU
  • 說明書:
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Drosophila melanogaster Voltage-dependent calcium channel type A subunit alpha-1(cac) ,partial
  • 貨號:
    CSB-MP310084DLU
  • 說明書:
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    cac
  • Uniprot No.:
  • 別名:
    cac; nbA; nonB; CG43368; Voltage-dependent calcium channel type A subunit alpha-1; Protein cacophony; Protein nightblind A; Protein no-on-transient B; Dmca1A
  • 種屬:
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, neurotransmitter release, gene expression, cell motility, cell division and cell death. Probably encodes a dihydropyridine-insensitive current. Vital for survival to adulthood.
  • 基因功能參考文獻:
    1. Motor defects in TDP-43 mutants can be rescued by expression of cacophony in motor neurons and by expression in two pairs of neurons in the brain. PMID: 28847811
    2. the novel R1673P allele of CACNA1A produces neurodegenerative phenotypes in flies and human, likely due to a toxic gain of function PMID: 28742085
    3. cacophony (cacTS2), a mutation of the Drosophila presynaptic Ca++ channel alpha1 subunit gene, is a particularly potent seizure-suppressor mutation, reverting seizure-like phenotypes for parabss1 and other BS mutants PMID: 26771829
    4. Cac regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis. PMID: 25811491
    5. Homeostatic depression is achieved by decreased presynaptic Cav2.1 calcium channel abundance and calcium influx. PMID: 25884248
    6. Dopaminergic neurons with mutant Ca2+ channel cacophony are inherently resistant to MPP+-induced neurodegeneration. PMID: 25445363
    7. cac and Dmca1D Ca(2+) channels differentially contribute to functional and structural aspects of slo-induced synaptic modifications PMID: 23959639
    8. Vesicle exocytosis depends on cacophony, TRP and TRPL. PMID: 22952921
    9. Homeostatic increase in Ca(2+) influx and release is blocked by a point mutation in the presynaptic CaV2.1 channel. PMID: 22633807
    10. role of mutation in courtship and other behaviors PMID: 12242229
    11. Dmca1A is an allele of the N-type calcium channel locus that caused synaptic undergrowth PMID: 12896973
    12. Localization of cacophony on presynaptic terminals at neuromuscular synapses. PMID: 14715960
    13. Data show that the Drosophila cacophony ts2 mutation reduces presynaptic Ca2+ entry and defines an important element in Cav2.1 channel inactivation PMID: 16820014
    14. These data confirm the presynaptic expression of synaptic homeostasis and implicate presynaptic Ca(V)2.1 in a homeostatic retrograde signaling system. PMID: 17114050
    15. Cacophony protein plays a key role in developmental regulation of Drosophila neuronal excitability. PMID: 17267561
    16. Neuronal overexpression of cac partially rescues the viability and physiological defects in stj mutants, indicating a role for the alpha(2)delta Ca(2+) channel subunit in mediating the proper localization of an alpha(1) subunit at synapses. PMID: 18391075
    17. cac encoded Ca(v)2-type calcium channels regulate action potential (AP)-independent release of neurotransmitter at excitatory cholinergic synapses PMID: 19004991

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Calcium channel alpha-1 subunit (TC 1.A.1.11) family
  • 組織特異性:
    Expressed widely in the embryonic nervous system.
  • 數(shù)據(jù)庫鏈接:

    KEGG: dme:Dmel_CG43368

    STRING: 7227.FBpp0298326

    UniGene: Dm.2395



主站蜘蛛池模板: 免费人成视频| 久久国产主播福利在线| 欧美性色大片在线观看| 夜晚成人18禁区导航网站| 国产精品久久| 亚洲精品无码久久久久久| 色欲色香天天天综合无码| 在线播放人成视频观看| 国产成人年无码av片在线观看| 人妻聚色窝窝人体www一区| 久久精品99久久香蕉国产色戒| 无码人妻精品一区二区三区不卡| 在线无码免费的毛片视频| 偷妻之寂寞难耐2中文字幕| 色欲香天天天综合网站| 大肉大捧一进一出视频| 亚洲性夜夜综合久久7777| 在线亚洲专区高清中文字幕| 极品少妇的粉嫩小泬视频| 日韩精品a片一区二区三区妖精| 无码人妻丰满熟妇区五十路在线| 欲色欲色天天天www| 女性高爱潮视频| 欧美一性一乱一交一视频| 国产高清视频色拍| 国产成人三级在线视频网站观看 | 无码精品一区二区三区免费视频| 真人抽搐一进一出视频| 亚洲午夜精品a片久久www慈禧| 99九九99九九视频精品| 亚洲bbw性色大片| 精品久久人人爽天天玩人人妻 | 成人欧美一区二区三区的电影| 亚洲精品久久久久中文第一幕| 天天做天天爱夜夜爽毛片| 动漫精品中文无码卡通动漫| 一区二区三区国产| 精品国产精品久久一区免费式| 欧美精品videossex另类日本| 亚洲卡一卡二乱码新区仙踪| 国产精品白浆一区二小说|