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  4. Recombinant Drosophila melanogaster Tyrosine-protein phosphatase non-receptor type 61F (Ptp61F), partial

Recombinant Drosophila melanogaster Tyrosine-protein phosphatase non-receptor type 61F (Ptp61F), partial

  • 中文名稱：
    黑腹果蠅Ptp61F重組蛋白
  • 貨號：
    CSB-YP895685DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅Ptp61F重組蛋白
  • 貨號：
    CSB-EP895685DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅Ptp61F重組蛋白
  • 貨號：
    CSB-EP895685DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅Ptp61F重組蛋白
  • 貨號：
    CSB-BP895685DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅Ptp61F重組蛋白
  • 貨號：
    CSB-MP895685DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Ptp61F
  • Uniprot No.：
  • 別名：
    Ptp61F; CG9181; Tyrosine-protein phosphatase non-receptor type 61F; EC 3.1.3.48; dPTP61F
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Non-receptor protein tyrosine phosphatase required for maintaining Dock in its non-phosphorylated state.
  • 基因功能參考文獻：
    1. Examination of the epistatic relationship between candidate genes and Stat92E reveals that Ptp61F and brm interact with Stat92E during both border cell specification and migration. PMID: 27175018
    2. Modulation of hyperactive MAP kinase activity by Ptp61F alleles, the phosphatase intervenes to directly or indirectly to regulate MAP kinase. PMID: 24752400
    3. The PTP61F variants differ in their capacities to regulate growth. PMID: 23339871
    4. Data show that more than 10,000 phosphorylation sites in the phosphoproteome were detected in Drosophila cells phosphatase Ptp61F knocked down by RNAi. PMID: 19429919
    5. identification of DPTP61F as responsible for maintaining Dock in its non-phosphorylated state PMID: 12014990
    6. These findings suggest that the reciprocal regulation of Abi phosphorylation by Abl and PTP61F may regulate the localization and stability of Abi and may regulate the formation of lamella. PMID: 17804420
    7. Ptp61F is a novel modulator of TOR activity PMID: 18653470
    8. Results establish that PTP61F and dAbl ensure proper actin organization through the coordinated and reversible tyrosine phosphorylation of Kette. PMID: 19398577

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  • 亞細胞定位：
    [Isoform A]: Cytoplasm. Endomembrane system. Note=Associates with the membranes of the reticular network and the mitochondria.; [Isoform B]: Nucleus.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class 1 subfamily
  • 組織特異性：
    Expressed during oogenesis and embryogenesis. Isoform A and isoform B are expressed in distinct patterns. Isoform B is expressed in the mesoderm and neuroblast layer during germband extension and later in the gut epithelia. Isoform A accumulates in 16 seg
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG9181

    STRING: 7227.FBpp0072602

    UniGene: Dm.1991



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