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  4. Recombinant Drosophila melanogaster Tyrosine-protein phosphatase corkscrew (csw), partial

Recombinant Drosophila melanogaster Tyrosine-protein phosphatase corkscrew (csw), partial

  • 中文名稱：
    Recombinant Drosophila melanogaster Tyrosine-protein phosphatase corkscrew(csw) ,partial
  • 貨號：
    CSB-YP326882DLU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Tyrosine-protein phosphatase corkscrew(csw) ,partial
  • 貨號：
    CSB-EP326882DLU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Tyrosine-protein phosphatase corkscrew(csw) ,partial
  • 貨號：
    CSB-EP326882DLU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Tyrosine-protein phosphatase corkscrew(csw) ,partial
  • 貨號：
    CSB-BP326882DLU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Tyrosine-protein phosphatase corkscrew(csw) ,partial
  • 貨號：
    CSB-MP326882DLU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    csw
  • Uniprot No.：
  • 別名：
    csw; CG3954Tyrosine-protein phosphatase corkscrew; EC 3.1.3.48
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Required in all receptor tyrosine kinase signaling pathways. Functions downstream of the receptor tyrosine kinase torso, acting in concert with D-Raf via tailless. Also functions downstream of Egfr (epidermal growth factor receptor) and btl (fibroblast growth factor receptor). The SH2 domain suggests that csw effects its role by mediating heteromeric protein interactions. Maternally required for normal determination of cell fates at the termini of the embryo. Required for cell fate specification of the ventral ectoderm, in the developing embryonic CNS and for embryonic tracheal cell migration. Functions during imaginal development for proper formation of adult structures such as eyes, aristae, L5 wing vein and the tarsal claw. Dephosphorylates drpr isoform A which is required for the inhibition by drpr isoform A of glial cell engulfment of axonal debris produced following axonal injury.
  • 基因功能參考文獻：
    1. Corkscrew/SHP-2 proteins control Sprouty phosphorylation and function PMID: 16481357
    2. LEOPARD syndrome mutations in csw gene have gain-of-function effects during Drosophila development. PMID: 18849586
    3. Study shows that in Drosophila, the duration of resting intervals required for inducing long-term memory is regulated by activity levels of the protein tyrosine phosphatase corkscrew (CSW). PMID: 19804763
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class subfamily
  • 組織特異性：
    Expressed uniformly throughout all tissues during embryogenesis.
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG3954

    STRING: 7227.FBpp0070363

    UniGene: Dm.5129



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