在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Drosophila melanogaster Tyrosine-protein kinase Src42A (Src42A), partial

Recombinant Drosophila melanogaster Tyrosine-protein kinase Src42A (Src42A), partial

  • 中文名稱：
    黑腹果蠅Src42A重組蛋白
  • 貨號：
    CSB-YP896060DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅Src42A重組蛋白
  • 貨號：
    CSB-EP896060DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅Src42A重組蛋白
  • 貨號：
    CSB-EP896060DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅Src42A重組蛋白
  • 貨號：
    CSB-BP896060DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅Src42A重組蛋白
  • 貨號：
    CSB-MP896060DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Src42A
  • Uniprot No.：
  • 別名：
    Src42A; Src41; TK5; CG44128; Tyrosine-protein kinase Src42A; EC 2.7.10.2; Tyrosine-protein kinase Src41; Dsrc41
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Required directly or indirectly for the phosphorylation of drpr which is necessary for the interaction of drpr with shark and subsequent glial phagocytic activity. Together with drpr and shark, promotes the migration of macrophages to sites of wounding as part of a signaling cascade where Scr42a detects production of hydrogen peroxide at wound sites which triggers phosphorylation of drpr and subsequent recruitment and activation of shark. Essential for correct eye morphogenesis (ommatidial R7 neuron formation) which requires the Ras1/MAPK signal transduction pathway. May be involved in the regulation of cytoskeleton organization and cell-cell contacts in developing ommatidia. During embryogenesis, involved in regulation of dorsal closure where it may have a role in activating the JNK pathway in leading edge cells during this process.
  • 基因功能參考文獻：
    1. Src overexpression alone activated the Jun N-terminal Kinase (JNK) signalling pathway to promote actin cytoskeletal and cell polarity defects and drive apoptosis in in a whole epithelial tissue context in the Drosophila eye, whereas, in cooperation with RasACT, JNK led to a loss of differentiation and an invasive phenotype. PMID: 29861494
    2. show the same signaling occurs in Drosophila inflammatory cells in response to wound-induced H2O2 with mutants for the Lyn homolog Src42A displaying impaired inflammatory migration to wounds PMID: 26028435
    3. Reduction of Src42A function leads to nuclear translocation and activation of FOXO proteins. PMID: 24513978
    4. Results show that Src42a and Src64b are required for the normal division capacity of Drosophila intestinal progenitor cells, and that these genes as well as Ack cause progenitor overproliferation in the intestine via core cell cycle activation. PMID: 24975577
    5. The tyrosine kinases Brk/PTK6/Sik, Srm, Frk/Rak/Gtk/Iyk/Bsk, and Src42A/Dsrc41 have a low degree of sequence homology to other known kinases. The exon structure of these kinases, called the Brk family, is highly conserved and distinct. PMID: 12725532
    6. Src42A is required (with Src64) for Armadillo tyrosine residue phosphorylation, and is essential for proper cell-cell matching during dorsal closure. PMID: 15857910
    7. Src42a is required for tracheal development and to increase the rate of adherens junction turnover. PMID: 18305002
    8. Draper-Src42A-Shark interactions are strikingly similar to mammalian immunoreceptor-SFK-Syk signalling events in mammalian myeloid and lymphoid cells. PMID: 18432193
    9. Genetic analyses imply that FAK mediates the signaling pathway of the alphaPS3 integrin and beta[nu] integrin heterodimer and functions redundantly with Src42A. PMID: 18925939

    顯示更多

    收起更多

  • 蛋白家族：
    Protein kinase superfamily, Tyr protein kinase family, SRC subfamily
  • 組織特異性：
    Ubiquitous in early embryos, in stages 13-16 expression is seen in visceral mesoderm, hindgut, brain, anal pads and ventral ganglions. In larvae, expression is in CNS, wing disk, leg disk and photoreceptor precursors in the eye-antenna disks posterior to
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG44128

    STRING: 7227.FBpp0085320

    UniGene: Dm.4134



主站蜘蛛池模板： 国产精品一区波多野结衣| 黑人强辱丰满的人妻熟女| 精品国产偷窥一区二区| 久久国产欧美日韩精品图片| 人妻avav中文系列久久| 亚洲乱码中文字幕小综合| 成人福利国产精品视频| 国产精品 视频一区 二区三区 | 国产成人免费爽爽爽视频| 大香线蕉伊人超碰| 在线观看国产丝袜控网站| 热99re久久精品这里都是精品| 国产精品毛片a∨一区二区三区| 一区二区三区高清日本vr| 欧美中文字幕无线码视频| 亚洲国产中文在线视频| 色综合久久一区二区三区| 久久久这里只有免费精品| 亚洲日韩高清在线亚洲专区| 久久国产午夜精品理论片34页| 国产香蕉97碰碰久久人人| 成人免费国产精品视频| 免费观看的av在线播放| 人妻av中文字幕一区二区三区| 正在播放国产剧情亂倫| 无码国产色欲xxxx视频| 无码av免费永久免费永久专区| 97se亚洲国产综合自在线| 人妻互换一二三区激情视频 | 亚洲偷自拍国综合色帝国| 小12箩利洗澡无码视频网站| 免费国精产品wnw2544| 欧美gv在线观看| 玩弄丰满熟妇xxxxx性60| 精品一区二区三区在线视频 | 国产成av人片在线观看天堂无码| 国产午夜无码片在线观看网站| 欧美日韩在线视频一区| 美女张开腿让人桶| 性av盈盈无码天堂| 国产在线一区二区三区四区五区|