在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Drosophila melanogaster Thioredoxin reductase 1, mitochondrial (Trxr-1), partial

Recombinant Drosophila melanogaster Thioredoxin reductase 1, mitochondrial (Trxr-1), partial

  • 中文名稱：
    黑腹果蠅Trxr-1重組蛋白
  • 貨號：
    CSB-YP310089DLU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅Trxr-1重組蛋白
  • 貨號：
    CSB-EP310089DLU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅Trxr-1重組蛋白
  • 貨號：
    CSB-BP310089DLU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅Trxr-1重組蛋白
  • 貨號：
    CSB-MP310089DLU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Trxr-1
  • Uniprot No.：
  • 別名：
    Trxr-1; GR; CG2151; Thioredoxin reductase 1; mitochondrial; TrxR-1; EC 1.8.1.9
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 表達區域：
    -
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Thioredoxin system is a major player in glutathione metabolism, due to the demonstrated absence of a glutathione reductase. Functionally interacts with the Sod/Cat reactive oxidation species (ROS) defense system and thereby has a role in preadult development and life span. Lack of a glutathione reductase suggests antioxidant defense in Drosophila, and probably in related insects, differs fundamentally from that in other organisms.
  • 基因功能參考文獻：
    1. Overexpression of mitochondrial TXNRD2 in Drosophila melanogaster extended median lifespan in female flies with a small lifespan extension in males; in contrast, overexpression of the cytosolic form, TXNRD1, did not produce a lifespan extension. PMID: 28474396
    2. Molecular orbital calculations suggested that the C-terminal hexapeptide Pro-Ala-Ser-Cys-Cys-Ser-OH functions as a redox center that alleviates the necessity for selenium in Dm-TrxR. PMID: 21389620
    3. mitochondrial and cytoplasmic variants are both essential for viability PMID: 11796729
    4. analysis of the mechanism of high Mr thioredoxin reductase from Drosophila melanogaster PMID: 12816954
    5. changing of His106 to asparagine, glutamine, and phenylalanine in various C-terminal mutants of Drosophila melanogaster thioredoxin reductase drops catalytic activity without change in pH profile PMID: 15670839
    6. X-ray crystal structure of thioredoxin reductase at 2.4 A resolution; demonstrated that tetrapeptides equivalent to the oxidized C-terminal active sites of both mouse mitochondrial TR (mTR3) and DmTR are substrates for the truncated forms of both enzymes PMID: 17385893
    7. redox potentials provide direct evidence for proposed catalytic mechanism of DmTrxR, & cast new light on essential role of DmTrx system in cycling GSSG/GSH & maintaining intracellular redox homeostasis in D. melanogaster without glutathione reductase. PMID: 17550271
    8. rates of steps in both the reductive and the oxidative half-reactions are markedly diminished in H464'Q thioredoxin reductase as compared to those of wild-type enzyme, indicating that His-464' is involved in both half-reactions PMID: 18211101
    9. the role of Glu-469' in catalysis by DmTrxR PMID: 18991392

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform B]: Mitochondrion.; [Isoform A]: Cytoplasm.
  • 蛋白家族：
    Class-I pyridine nucleotide-disulfide oxidoreductase family
  • 組織特異性：
    During embryogenesis, expression is seen in germ cell progenitors, developing midgut, hindgut and proventriculus.
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG2151

    STRING: 7227.FBpp0071116

    UniGene: Dm.20991



主站蜘蛛池模板： 无码人妻一区二区三区一| 无码孕妇孕交在线观看| av老司机亚洲精品天堂| 亚洲欧洲无码一区二区三区| 久久综合少妇11p| 无码专区手机在线播放| 亚洲男人第一av网站| 午夜天堂精品久久久久| 粉嫩粉嫩的18在线观看| 亚洲另类欧美在线电影| 精品人无码一区二区三区| 欧洲成人一区二区三区| 99re6热精品视频在线观看| 国产精品毛片av999999| 国语自产精品视频在线看| 最新国产乱人伦偷精品免费网站| 三上悠亚的av片在线无码| 国产欧美日韩亚洲18禁在线| 亚洲 国产 韩国 欧美 在线| 国产精品无码久久久久成人影院| 国产精品亚洲а∨天堂网| 亚洲中文精品久久久久久| 国产成人精品一区二三区| www国产精品内射老熟女| 变态另类先锋影音| 我的性奴的肉玩具1一17心奴| 欧美人妻日韩精品| 亚洲 日韩 国产 中文有码| 亚洲精品一区二区中文字幕| 亚洲女同一区二区| 老司机午夜免费精品视频| 女高中生第一次破苞av| 激情综合丁香五月| 日本高清在线一区二区三区| 黄网站色成年片在线观看| 色琪琪av中文字幕一区二区| 99国产精品久久久久久久日本竹| 亚洲国产av玩弄放荡人妇系列| 青娱国产区在线| 无码人妻丝袜在线视频| 色综合av综合无码综合网站|