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  4. Recombinant Drosophila melanogaster Telomere-binding protein cav (cav)

Recombinant Drosophila melanogaster Telomere-binding protein cav (cav)

  • 中文名稱：
    Recombinant Drosophila melanogaster Telomere-binding protein cav(cav)
  • 貨號：
    CSB-YP853321DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Telomere-binding protein cav(cav)
  • 貨號：
    CSB-EP853321DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Telomere-binding protein cav(cav)
  • 貨號：
    CSB-EP853321DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Telomere-binding protein cav(cav)
  • 貨號：
    CSB-BP853321DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Telomere-binding protein cav(cav)
  • 貨號：
    CSB-MP853321DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    cav
  • Uniprot No.：
  • 別名：
    cav; anon; fe; 1G5; anon1G5; Hoap; IG5; CG6219; Telomere-binding protein cav; Anonymous fast evolving 1G5; HP1/ORC-associated protein; HOAP p55; Protein caravaggio
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-345
  • 氨基酸序列
    MLLLLCVNMS GTQMSAFLRK YLADEDKKIR AQFKESDPNN KLILWMHEKT RITEEDLARP YTEDEVKELC LRTKVKVDMT AWNCLWEAKK RFEAKGRFVN KSERFINRMY MKAVRRKMVQ PYPEEFVAQR REIVAAETKK QNISRLDRWQ KKKSQNLSAP ESSPDAHASS NDAVQSHEDQ ANTNLSSLSQ MNFQVEAMAP PGVSSSDLSG IGDDEDEQQQ SGFQDENINR PETEINENSV RCDPINLGRM RTGCINSQAN NSFRNTESDP DYYMFGTQLS TLVRPTSTQE PDDQVNCPET EMNESWVRCD QINSESLSIG PSIDSEGTIT FQNTESEPID VTSIA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping.
  • 基因功能參考文獻：
    1. genetic and biochemical assays indicate a repressing activity for HOAP PMID: 21695246
    2. HOAP has a role in functional centric heterochromatin PMID: 12826664
    3. HOAP-depleted telomeres activate both the DNA-damage response and the spindle assembly checkpoint. PMID: 18246067
    4. Drosophila modigliani (moi) gene encodes a HOAP-interacting protein required for telomere protection PMID: 19181850
    5. HOAP interacts with Umbrea with functional role in mediating normal telomere behaviour in Drosophila PMID: 19190990

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  • 亞細胞定位：
    Nucleus. Chromosome, telomere.
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG6219

    STRING: 7227.FBpp0083943

    UniGene: Dm.20244



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