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  4. Recombinant Drosophila melanogaster Sodium channel protein 60E (NaCP60E), partial

Recombinant Drosophila melanogaster Sodium channel protein 60E (NaCP60E), partial

  • 中文名稱：
    黑腹果蠅NaCP60E重組蛋白
  • 貨號：
    CSB-YP892926DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅NaCP60E重組蛋白
  • 貨號：
    CSB-EP892926DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅NaCP60E重組蛋白
  • 貨號：
    CSB-EP892926DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅NaCP60E重組蛋白
  • 貨號：
    CSB-BP892926DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅NaCP60E重組蛋白
  • 貨號：
    CSB-MP892926DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    NaCP60E
  • Uniprot No.：
  • 別名：
    NaCP60E; DIC60; DSC1; smi60E; CG34405; Sodium channel protein 60E; Drosophila ion channel 60; Drosophila sodium channel 1; Protein smell-impaired 60E; Sodium channel 2; DmNav2
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Mediates the voltage-dependent sodium ion permeability of excitable membranes. Plays a role in processing of olfactory information during the olfactory avoidance response.
  • 基因功能參考文獻：
    1. We summarize major findings from recent studies and highlight a unique role of the DSC1 channel, distinct from that of the sodium channel, in regulating membrane excitability and modulating toxicity of pyrethroid insecticides PMID: 25987218
    2. These results reveal an important role of the DSC1 channel in modulating the stability of neural circuits, particularly under environmental stresses, likely by maintaining the sustainability of synaptic transmission. PMID: 23505382
    3. DSC1 channels are expressed in both the central and the peripheral nervous system of adult Drosophila melanogaster. PMID: 12488978
    4. These results identify nebula/DSCR1 as a regulator of mitochondrial function and integrity and further suggest that an increased level of DSCR1 may contribute to the mitochondrial dysfunction seen in Down syndrome. PMID: 16222229
    5. This study showed that transcripts lacking all cytoplasmic alternatively spliced exons still produce functional channels' PMID: 19625535

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  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Sodium channel (TC 1.A.1.10) family, NaCP60E subfamily
  • 組織特異性：
    In embryonic and larval stages, expression is limited to very few non-neuronal cells in either the CNS or PNS. In pupal and adult stages, expressed in cell bodies of the fly central nervous system, including optic lobes, central brain, subesophageal gangl
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG34405

    STRING: 7227.FBpp0303273

    UniGene: Dm.20002



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