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  4. Recombinant Drosophila melanogaster RuvB-like helicase 1 (pont)

Recombinant Drosophila melanogaster RuvB-like helicase 1 (pont)

  • 中文名稱：
    黑腹果蠅pont重組蛋白
  • 貨號：
    CSB-YP893279DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅pont重組蛋白
  • 貨號：
    CSB-EP893279DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅pont重組蛋白
  • 貨號：
    CSB-EP893279DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅pont重組蛋白
  • 貨號：
    CSB-BP893279DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅pont重組蛋白
  • 貨號：
    CSB-MP893279DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    pont
  • Uniprot No.：
  • 別名：
    pont; CG4003; RuvB-like helicase 1; EC 3.6.4.12; Dpontin; Dpon; Pontin
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-456
  • 氨基酸序列
    MKIEEVKSTV RTQRIAAHSH VKGLGLDEVG AAVHSAAGLV GQKAAREAAG IVVDLIKSKK MAGRALLLAG PPGTGKTAIA LAIAQELGNK VPFCPMVGSE VFSNEIKKTE VLMENFRRSI GLRIRETKEV YEGEVTELTP VETENPMGGY GKTISNVVIG LKTAKGTKQL KLDPSIFDAL QKEKVEVGDV IYIEANSGAV KRQGRSDTFA TEFDLETEEY VPLPKGDVHK KKEVIQDVTL HDLDVANARP QGGQDVLSMM GQLMKPKKTE ITDKLRMEIN KVVNKYIDQG IAELVPGVLF IDEIHMLDLE TFTYLHKSLE SPIAPIVIFA TNRGRCVIRG TTDIVSPHGI PLDLLDRLLI IRTLLYSTAD MEQIIKLRAQ TEGLQLEENA FTRLSEIGTS STLRYAVQLL TPAHQMCKVN GRNQISKDDI EDVHSLFLDA KRSSKHLSEK NNKFML
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts as a transcriptional coactivator in Wg signaling caused by altered arm signaling. Pont and rept interfere antagonistically with nuclear arm signaling function, and are required to enhance or reduce arm activity, respectively. Also an essential cofactor for the normal function of Myc; required for cellular proliferation and growth.; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
  • 基因功能參考文獻(xiàn)：
    1. Pontin has a mitosis-specific function in regulating microtubule assembly PMID: 18463163
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    RuvB family
  • 組織特異性：
    Higher expression occurs in primordia of mesoderm, anterior and posterior midgut and cephalic furrow early in gastrulation, as well as in endoderm and mesoderm lineages during germ band extension. Later in development expression is only maintained in endo
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG4003

    STRING: 7227.FBpp0081704

    UniGene: Dm.1557



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