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  4. Recombinant Drosophila melanogaster RNA-binding protein cabeza (caz)

Recombinant Drosophila melanogaster RNA-binding protein cabeza (caz)

  • 中文名稱：
    Recombinant Drosophila melanogaster RNA-binding protein cabeza(caz)
  • 貨號：
    CSB-YP631662DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster RNA-binding protein cabeza(caz)
  • 貨號：
    CSB-EP631662DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster RNA-binding protein cabeza(caz)
  • 貨號：
    CSB-EP631662DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster RNA-binding protein cabeza(caz)
  • 貨號：
    CSB-BP631662DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster RNA-binding protein cabeza(caz)
  • 貨號：
    CSB-MP631662DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    caz
  • Uniprot No.：
  • 別名：
    caz; SARFH; CG3606RNA-binding protein cabeza; P19; Sarcoma-associated RNA-binding fly homolog
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-399
  • 氨基酸序列
    MERGGYGGGS GQGYNNFAVP PPNYQQMPNK TGNYNEPPPN YGKQGGGYDS GSGHRGSGGS GNGGGGGGSW NDRGGNSYGN GGASKDSYNK GHGGYSGGGG GGGGGGGGGS GGNDMITQED TIFVSGMDPS TTEQDIETHF GAIGIIKKDK RTMKPKIWLY KNKETGASKG EATVTYDDTN AAQSAIEWFD GRDFNGNAIK VSLAQRQNNW NKGGGGGGGG GGRGGFGGRR GGGGGGGGGG GGGGRFDRGG GGGGGRYDRG GGGGGGGGGG NVQPRDGDWK CNSCNNTNFA WRNECNRCKT PKGDDEGSSG GGGGGGYGGG GGGGGYDRGN DRGSGGGGYH NRDRGGNSQG GGGGGGGGGG YSRFNDNNGG GRGGRGGGGG NRRDGGPMRN DGGMRSRPY
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May participate in a function common to the expression of most genes transcribed by RNA polymerase II.
  • 基因功能參考文獻：
    1. Results that the molecular mechanisms controlling the nuclear import of FUS/Caz and FUS autoregulation are conserved between humans and Drosophila PMID: 25447237
    2. Data demonstrate that FUS/Caz regulates neuromuscular junction development and plays an evolutionarily conserved role in modulating the strength of synaptic transmission in motor neurons. PMID: 24569165
    3. The loss of caz in Drosophila led to severe growth defects in the eyes and ventral nerve cords, caused locomotive disability and neuromuscular junction disruption, but did not induce apoptotic cell death. PMID: 22443542
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    RRM TET family
  • 組織特異性：
    Ubiquitous. Enriched in the brain and central nervous system during embryogenesis. Enriched in the adult head. Embryos contain both isoforms A and B, whereas later in development (heads and torsos) only isoform B is detected.
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG3606

    STRING: 7227.FBpp0073996

    UniGene: Dm.2872



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