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  4. Recombinant Drosophila melanogaster RNA-binding protein 8A (tsu)

Recombinant Drosophila melanogaster RNA-binding protein 8A (tsu)

  • 中文名稱：
    黑腹果蠅tsu重組蛋白
  • 貨號：
    CSB-YP894181DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅tsu重組蛋白
  • 貨號：
    CSB-EP894181DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅tsu重組蛋白
  • 貨號：
    CSB-EP894181DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅tsu重組蛋白
  • 貨號：
    CSB-BP894181DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅tsu重組蛋白
  • 貨號：
    CSB-MP894181DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    tsu
  • Uniprot No.：
  • 別名：
    tsu; Y14; CG8781; RNA-binding protein 8A; Protein tsunagi
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-165
  • 氨基酸序列
    MADVLDIDNA EEFEVDEDGD QGIVRLKEKA KHRKGRGFGS DSNTREAIHS YERVRNEDDD ELEPGPQRSV EGWILFVTSI HEEAQEDEIQ EKFCDYGEIK NIHLNLDRRT GFSKGYALVE YETHKQALAA KEALNGAEIM GQTIQVDWCF VKGPKRVKKS EKRRR
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. Involved in exon definition of genes containing long introns, including the rolled/MAPK gene. The mago-tsu heterodimer interacts with the EJC key regulator Pym leading to EJC disassembly in the cytoplasm. Has a role in oskar mRNA localization to the posterior pole of the developing oocyte.
  • 基因功能參考文獻：
    1. Tsunagi/Y14 forms compllex with Mago Nashi and Ranshi protein that influences oocyte differentiation in Drosophila melanogaster. PMID: 20045686
    2. We have determined the crystal structure of the complex between Drosophila melanogaster Y14 and Mago at a resolution of 2.5 A. The structure reveals an atypical mode of protein-protein recognition mediated by an RNA-binding domain (RBD). PMID: 12730685
    3. Tsunagi/Y14 is essential for restricting oocyte fate to a single cell and may function with mago nashi in this process. PMID: 17628520
  • 亞細胞定位：
    Nucleus. Cytoplasm. Note=Part of the EJC assembled on mRNAs in the nucleus and remains part of the complex when mRNA moves into the cytoplasm.
  • 蛋白家族：
    RBM8A family
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG8781

    STRING: 7227.FBpp0087648

    UniGene: Dm.19884



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