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  4. Recombinant Drosophila melanogaster Protein rhomboid (rho), partial

Recombinant Drosophila melanogaster Protein rhomboid (rho), partial

  • 中文名稱：
    黑腹果蠅rho重組蛋白
  • 貨號(hào)：
    CSB-YP323222DLU1
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅rho重組蛋白
  • 貨號(hào)：
    CSB-EP323222DLU1
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅rho重組蛋白
  • 貨號(hào)：
    CSB-EP323222DLU1-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅rho重組蛋白
  • 貨號(hào)：
    CSB-BP323222DLU1
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅rho重組蛋白
  • 貨號(hào)：
    CSB-MP323222DLU1
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    rho; Ve; CG1004; Protein rhomboid; Protein veinlet
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts early in embryonic development to establish position along the dorsoventral axis and then again later to specify the fate of neuronal precursor cells. Involved in EGF receptor signaling; cleaves Spitz to release the active growth factor.
  • 基因功能參考文獻(xiàn)：
    1. a rhomboid enhancer element that selectively labels four Drosophila embryonic neural precursors, was characterized. PMID: 26252385
    2. Structure and mechanism of rhomboid protease. PMID: 23585569
    3. analysis of EGFR-dependent network interactions that pattern Drosophila eggshell appendages; each appendage is derived from a primordium comprising a patch of cells expressing broad (br) and an adjacent stripe of cells expressing rhomboid (rho) PMID: 22782725
    4. Drosophila RHO is the founder member of a previously undescribed family of serine proteases, and could be directly responsible for the unusual, intramembranous cleavage of EGFr ligands. PMID: 12221285
    5. A key component of mitochondrial fusion, Mgm1p, is activated by a novel mitochondrial endopeptidase related to this Drosophila melanogaster signaling protein. PMID: 12776123
    6. Substrate specificity of RHO intramembrane protease is governed by helix-breaking residues in the transmembrane domain. PMID: 12820957
    7. Evolution of the trans-regulatory environment that controls rho expression in somatic follicle cells could be a major contributor to the evolutionary changes in DA number. PMID: 17360774
    8. rhomboid may function in R8 cells to activate Epidermal growth factor receptor signaling in R7 cells PMID: 19261861

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  • 亞細(xì)胞定位：
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Peptidase S54 family
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: dme:Dmel_CG1004

    STRING: 7227.FBpp0305409

    UniGene: Dm.808



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