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  4. Recombinant Drosophila melanogaster Protein asunder (Asun), partial

Recombinant Drosophila melanogaster Protein asunder (Asun), partial

  • 中文名稱：
    Recombinant Drosophila melanogaster Protein asunder(Asun) ,partial
  • 貨號：
    CSB-YP894682DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Protein asunder(Asun) ,partial
  • 貨號：
    CSB-EP894682DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Protein asunder(Asun) ,partial
  • 貨號：
    CSB-EP894682DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Protein asunder(Asun) ,partial
  • 貨號：
    CSB-BP894682DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Protein asunder(Asun) ,partial
  • 貨號：
    CSB-MP894682DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Asun
  • Uniprot No.：
  • 別名：
    Asun; IntS13; Mat89Bb; ovary2; CG6814; Protein asunder; Cell cycle regulator Mat89Bb; Integrator complex subunit 13; Maternal transcript 89Bb; Set apart in position or space protein
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box-dependent processing. Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1 and U5. Plays a role as a regulator of spermatogenesis. Crucial regulator of the mitotic cell cycle and development. Required for the correct dynein-dynactin perinuclear localization important for nucleus-centrosome coupling that occur upon meiotic progression of primary spermatocytes. Plays a role in sperm motility and fertility. May have a role in the PNG/PLU/GNU pathway.
  • 基因功能參考文獻：
    1. ASUN is identified as a functional component of Integrator (INT), a multisubunit complex required for 3'-end processing of small nuclear RNAs. PMID: 23904267
    2. asun is a critical regulator of dynein localization and dynein-mediated processes during Drosophila oogenesis PMID: 24333177
    3. asunder(previously Mat89Bb)required for male fertility; asun spermatocytes & spermatids exhibit reduction of perinuclear dynein-dynactin; model proposed in which asun coordinates spermatogenesis by promoting dynein-dynactin recruitment to nuclear surface PMID: 19357193
  • 亞細胞定位：
    Nucleus. Cytoplasm. Cytoplasm, perinuclear region.
  • 蛋白家族：
    Asunder family
  • 組織特異性：
    Expressed in nurse cells at stages 9-10 of oogenesis and exported to the oocyte. Also expressed in the follicle cells surrounding the oocyte.
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG6814

    STRING: 7227.FBpp0082713

    UniGene: Dm.2414



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