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  4. Recombinant Drosophila melanogaster Nucleosome-remodeling factor subunit NURF301 (E (bx)), partial

Recombinant Drosophila melanogaster Nucleosome-remodeling factor subunit NURF301 (E (bx)), partial

  • 中文名稱：
    黑腹果蠅E(bx)重組蛋白
  • 貨號(hào)：
    CSB-YP893829DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅E(bx)重組蛋白
  • 貨號(hào)：
    CSB-EP893829DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅E(bx)重組蛋白
  • 貨號(hào)：
    CSB-EP893829DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅E(bx)重組蛋白
  • 貨號(hào)：
    CSB-BP893829DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅E(bx)重組蛋白
  • 貨號(hào)：
    CSB-MP893829DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    E(bx)
  • Uniprot No.：
  • 別名：
    E(bx); CG32346; CG7022; Nurf301Nucleosome-remodeling factor subunit NURF301; Enhancer of bithorax; Nucleosome-remodeling factor 215 kDa subunit; NURF-215
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Histone-binding component of NURF (nucleosome remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. Required for homeotic gene expression, proper larval blood cell development, normal male X chromosome morphology, ecdysteroid signaling and metamorphosis.
  • 基因功能參考文獻(xiàn)：
    1. The data show that, besides anticipated roles at enhancers, NURF interacts physically and functionally with the TRF2/DREF basal transcription factor to organize nucleosomes downstream of active promoters. PMID: 27046080
    2. required for stem cell maintenance in the Drosophila testis PMID: 20569693
    3. Chromatin immunoprecipitation localizes NURF to Ken-binding sites in hemocytes, suggesting that Ken recruits NURF. PMID: 18334252
    4. Study demonstrates that three NURF301 isoforms are expressed and that these encode functionally distinct NURF chromatin remodeling complexes. PMID: 19629165
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    BPTF family
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: dme:Dmel_CG32346

    STRING: 7227.FBpp0304412

    UniGene: Dm.1449



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