在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Drosophila melanogaster Histone-lysine N-methyltransferase ash1 (ash1), partial

Recombinant Drosophila melanogaster Histone-lysine N-methyltransferase ash1 (ash1), partial

  • 中文名稱：
    Recombinant Drosophila melanogaster Histone-lysine N-methyltransferase ash1(ash1) ,partial
  • 貨號(hào)：
    CSB-YP895203DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Histone-lysine N-methyltransferase ash1(ash1) ,partial
  • 貨號(hào)：
    CSB-EP895203DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Histone-lysine N-methyltransferase ash1(ash1) ,partial
  • 貨號(hào)：
    CSB-EP895203DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Histone-lysine N-methyltransferase ash1(ash1) ,partial
  • 貨號(hào)：
    CSB-BP895203DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Histone-lysine N-methyltransferase ash1(ash1) ,partial
  • 貨號(hào)：
    CSB-MP895203DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ash1
  • Uniprot No.：
  • 別名：
    ash1; KMT2H; CG8887; Histone-lysine N-methyltransferase ash1; EC 2.1.1.354; Absent small and homeotic disks protein 1; Lysine N-methyltransferase 2H
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Trithorax group (TrxG) protein that has histone methyltransferase activity. Specifically trimethylates 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. TrxG proteins are generally required to maintain the transcriptionally active state of homeotic genes throughout development. Does not act as a coactivator required for transcriptional activation, but specifically prevents inappropriate Polycomb Group (PcG) silencing of homeotic genes in cells in which they must stay transcriptionally active.
  • 基因功能參考文獻(xiàn)：
    1. Mrg15 is a subunit of the Ash1 complex, a stimulator of Ash1 enzymatic activity and a critical regulator of the TrxG protein function of Ash1 in Drosophila. PMID: 29158494
    2. Ash1 HMTase activity is activated by MRG15, a subunit of the identified Ash1 complex, and that this complex, rather than the Ash1 protein alone, is the active form of this H3K36 methyltransferase, both in vitro and in vivo. PMID: 29540501
    3. If ASH1 or TRX function is lost or reduced, heterochromatin can spread into these domains creating a sink that diverts heterochromatic proteins from other variegating locations, which then may express a suppressed phenotype. PMID: 27373142
    4. Physical interaction of ASH1 with FSH activates global transcription. PMID: 23442797
    5. loss of ASH1 significantly decreases H3K36 dimethylation, providing further evidence that ASH1 is an H3K36 dimethylase in vivo. PMID: 24004944
    6. implication that ASH1 is required for essentially all H3-K4 methylation that occurs in vivo PMID: 13679578
    7. lysine to arginine substitution of histone H3 at position 36 abolished the methyltransferase activity of Drosophila ASH1, suggesting that K36 is their specific target PMID: 17544230

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, SET2 subfamily
  • 組織特異性：
    Expressed throughout development but is present at higher levels during the embryonic and pupal stages than during the larval stages. During the larval stages it accumulates primarily in imaginal disks.
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG8887

    STRING: 7227.FBpp0297151

    UniGene: Dm.7698



主站蜘蛛池模板： 成人无码男男gv在线观看网站| 无码国模大尺度视频在线观看| 亚洲人成无码网www动漫| 国产老太睡小伙子视频| 18禁黄网站禁片免费观看女女| 久久97久久97精品免视看| 国语自产精品视频在线看| 乌克兰少妇videos高潮| 欧美熟妇xxxxx欧美老妇不卡| 亚欧成a人无码精品va片| 国产 高潮 抽搐 正在播放| 欧美性性性性o00xx| 国产精品亚洲a∨天堂| 久久国产乱子伦免费精品| 免费又黄又硬又爽大片| 国产精品毛片a∨一区二区三区| 狠狠久久噜噜熟女| 蜜色欲多人av久久无码| 亚洲色播永久网址大全| 精品卡一卡二卡3卡高清乱码| 国模无码视频一区二区三区| 人妻无码一区二区三区 tv| 亚洲国产综合av在线观看| 国产一区二区不卡在线看| 久久中文字幕人妻熟女| 蜜臀av夜夜澡人人爽人人| 无遮挡国产高潮视频免费观看 | 国产又爽又黄无码无遮挡在线观看| 精品香蕉久久久午夜福利| 国产亚洲精品久久久ai换脸| 正在播放国产乱子伦最新视频 | 天天爽天天爽天天片a| 国产精品久久无码一区| 色先锋av影音先锋在线| 妺妺跟我一起洗澡没忍住| av天堂久久精品影音先锋| 国产日产精品一区二区三区四区的特点 | 伊人狠狠色丁香婷婷综合| 中文无码精品a∨在线观看| 免费永久在线观看黄网站| 欧美人和黑人牲交网站上线|