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  4. Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B3 (CycB3), partial

Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B3 (CycB3), partial

  • 中文名稱：
    Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B3(CycB3) ,partial
  • 貨號：
    CSB-YP888240DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B3(CycB3) ,partial
  • 貨號：
    CSB-EP888240DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B3(CycB3) ,partial
  • 貨號：
    CSB-EP888240DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B3(CycB3) ,partial
  • 貨號：
    CSB-BP888240DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B3(CycB3) ,partial
  • 貨號：
    CSB-MP888240DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CycB3
  • Uniprot No.：
  • 別名：
    CycB3; CG5814; G2/mitotic-specific cyclin-B3
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Cyclins are positive regulatory subunits of the cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Probably functions redundantly with other cyclins in regulation of cell cycle. Its presence may be required to delay a deadline for completing cytokinesis that is ordinary imposed by nuclear envelope reformation. Degradation of CycB and CycB3 promote cytokinesis furrow initiation and ingression. Required with CycB for female fertility.
  • 基因功能參考文獻：
    1. overexpression of cycB3 dramatically increases the cystoblast(CB) number in Drosophila ovaries, suggesting that an excess of cycB3 function delays CB differentiation. Given that the cycB3 gene is evolutionarily conserved, from insects to humans, cycB3 may also be involved in controlling the fate of germline stem cells in humans. PMID: 29351213
    2. Changing Cyclin B3 levels showed that it accelerated progress to anaphase, even in the absence of spindle assembly checkpoint function. PMID: 25754637
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Cyclin family, Cyclin AB subfamily
  • 組織特異性：
    In embryo, it is expressed in all mitotically proliferating cells, with a high level in neuroblasts. Not expressed in old embryos and thereafter. Not expressed in endoreplicating tissues.
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG5814

    STRING: 7227.FBpp0084103

    UniGene: Dm.3241



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