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  4. Recombinant Drosophila melanogaster Fringe glycosyltransferase (fng), partial

Recombinant Drosophila melanogaster Fringe glycosyltransferase (fng), partial

  • 中文名稱：
    黑腹果蠅fng重組蛋白
  • 貨號：
    CSB-YP631542DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅fng重組蛋白
  • 貨號：
    CSB-EP631542DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅fng重組蛋白
  • 貨號：
    CSB-EP631542DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅fng重組蛋白
  • 貨號：
    CSB-BP631542DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅fng重組蛋白
  • 貨號：
    CSB-MP631542DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    fng
  • Uniprot No.：
  • 別名：
    fng; CG10580Fringe glycosyltransferase; EC 2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Glycosyltransferase involved in the elongation of O-linked ligands to activate Notch signaling. Possesses fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity; extends the O-linked fucose on the Notch EGF repeats. Boundary-specific cell-signaling molecule that is responsible for dorsal-ventral cell interactions during wing development.
  • 基因功能參考文獻：
    1. Mapping Sites of O-Glycosylation and Fringe Elongation on Drosophila Notch. PMID: 27268051
    2. FOXO-mediated regulation of fringe links the insulin and Notch signaling pathways in the germline stem cell niche. PMID: 23895933
    3. molecular genetic analysis PMID: 12743367
    4. suppresses effects of OFUT1 on Notch binding; decreases Serrate-Notch binding but increases Delta-Notch binding. PMID: 12909620
    5. Fringe is required in the stretched cells and the anterior main body follicular cells to control stretched cell number and the timing of main body follicular cell displacement. PMID: 17420294

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  • 亞細胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 31 family
  • 組織特異性：
    Expressed in dorsal cells.
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG10580

    STRING: 7227.FBpp0077925

    UniGene: Dm.4336



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