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  4. Recombinant Drosophila melanogaster Adipokinetic hormone (Akh)

Recombinant Drosophila melanogaster Adipokinetic hormone (Akh)

  • 中文名稱：
    Recombinant Drosophila melanogaster Adipokinetic hormone(Akh)
  • 貨號：
    CSB-YP351100DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Adipokinetic hormone(Akh)
  • 貨號：
    CSB-EP351100DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Adipokinetic hormone(Akh)
  • 貨號：
    CSB-EP351100DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Adipokinetic hormone(Akh)
  • 貨號：
    CSB-BP351100DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Adipokinetic hormone(Akh)
  • 貨號：
    CSB-MP351100DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Akh
  • Uniprot No.：
  • 別名：
    Akh; CG1171Adipokinetic hormone; Hypertrehalosaemic hormone; HRTH; dAKH
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Cytoplasmic domain
  • 表達區域：
    23-30
  • 氨基酸序列
    QLTFSPDW
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Probably causes a marked increase in hemolymph carbohydrate.
  • 基因功能參考文獻：
    1. Data (including data from studies using transgenic and mutant strains) suggest that Akh plays role in control of energy metabolism in this species; lipids appear to be main energy reserve during starvation; once glycogen stores are exhausted, carbohydrates are synthesized from other sources. PMID: 30110658
    2. During adulthood, however, AKH regulates body fat content and the hemolymph sugar level as well as nutritional and oxidative stress responses. Finally, we provide evidence for a negative autoregulatory loop in Akh gene regulation. PMID: 26275422
    3. Akh is an important regulator of metabolic homeostasis in Drosophila PMID: 25641265
    4. AKH signaling is required in insulin-producing cells for sugar-dependent Dilp3 release. PMID: 25882208
    5. Data (including data from studies using transgenic flies) suggest that FoxO (forkhead box sub-group O) acts downstream of AKH (adipokinetic hormone) as transcription factor to mediate response to oxidative stress. PMID: 25814322
    6. Molecular identification of the insect adipokinetic hormone receptors PMID: 11904407
    7. Identification of G protein-coupled receptors for Drosophila supports a theory of ligand-receptor coevolution. PMID: 12177421
    8. AKH has a role in the regulation of starvation-induced foraging behavior PMID: 15166157

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    AKH/HRTH/RPCH family
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG1171

    STRING: 7227.FBpp0073069

    UniGene: Dm.23971



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