在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Dog Tight junction protein ZO-2 (TJP2), partial

Recombinant Dog Tight junction protein ZO-2 (TJP2), partial

  • 中文名稱：
    熟悉的犬TJP2重組蛋白
  • 貨號：
    CSB-YP839157DO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    熟悉的犬TJP2重組蛋白
  • 貨號：
    CSB-EP839157DO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    熟悉的犬TJP2重組蛋白
  • 貨號：
    CSB-EP839157DO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    熟悉的犬TJP2重組蛋白
  • 貨號：
    CSB-BP839157DO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    熟悉的犬TJP2重組蛋白
  • 貨號：
    CSB-MP839157DO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    TJP2
  • Uniprot No.：
  • 別名：
    TJP2; ZO2; Tight junction protein ZO-2; Tight junction protein 2; Zona occludens protein 2; Zonula occludens protein 2
  • 種屬：
    Canis familiaris (Dog) (Canis lupus familiaris)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in tight junctions and adherens junctions.
  • 基因功能參考文獻：
    1. Silencing tight junction protein ZO-2 alters epithelial cytoarchitecture.ZO-2 silencing increases RhoA activity through GEF-H1 recruitment to cell borders.ZO-2 silencing activates Cdc42 and triggers mitotic spindle disorientation. ZO-2 silencing increases Rac1 and cofilin activity and lamellipodia formation. PMID: 28554775
    2. SUMOylation affects the intracellular localization of ZO-2 and its regulatory role on GSK3beta and beta-catenin signaling activity. PMID: 27604867
    3. novel posttranslational modifications of ZO-2 regulate the intracellular fate of this protein. PMID: 23804652
    4. ZO-1 and ZO-2 proteins are required not only for TJ assembly but also for regulating the organization and functional activity of the apical cytoskeleton, particularly the perijunctional actomyosin ring; these activities are relevant both to cellular organization and epithelial morphogenesis. PMID: 22190737
    5. The identification of ZASP helps to unfold the complex nuclear molecular arrays that form on ZO-2 scaffolds. PMID: 20868680
    6. The canine sequence of ZO-2 displays four putative nuclear export signals (NES), two at the second PDZ domain (NES-0 and NES-1) and the rest at the guanylate kinase region (NES-2 and NES-3). PMID: 16920099
    7. ZO-2 silencing triggered: changes in the gate function of the TJ, changes in the fence function of the TJ; altered expression of TJ and adherens junction proteins, an atypical monolayer architecture. PMID: 17374535
    8. Constitutive expression in MDCK cells, GP8 endothelial cells nuclei leads to increase expression of the M2 pyruvate kinase,increased proliferative activity and in MDCK reduced intercellular junctional stability. PMID: 17973926
    9. ZO-2 inhibits cell proliferation at G0/G1 and decreases CD1 protein level. PMID: 19056685
    10. The departure of ZO-2 from the nucleus is regulated by phosphorylation at Ser369 by novel PKCepsilon. PMID: 19625451

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Cell junction, tight junction.
  • 蛋白家族：
    MAGUK family
  • 數據庫鏈接：


主站蜘蛛池模板： 色88久久久久高潮综合影院| 中文亚洲无线码49vv| 狠狠色色综合站| 国产交换配乱婬视频| 精品国产乱码久久久久久郑州公司 | 无码日韩人妻精品久久| 国产成人午夜福利在线观看| 婷婷五月日韩av永久免费| 成在线人免费视频播放| 人妻熟妇乱又伦精品hd| 色婷婷综合中文久久一本| 中文字幕亚洲乱码熟女在线| 久久香蕉国产线看观看手机| 亚洲国产老鸭窝一区二区三区| 亚洲综合欧美在线一区在线播放| 76少妇精品导航| 欧美裸体xxxx极品少妇| 国产精品白浆在线观看免费 | 粉嫩被粗大进进出出视频| 免费人成黄页在线观看国产| 国产成人亚洲综合无码| 国产精品白浆一区二小说| 一出一进一爽一粗一大视频免费的 | 7m精品福利视频导航| 久久综合久久88中字幕文| 永久黄网站色视频免费看| 毛片无码国产| 一性一交一口添一摸视频 | 一本一道色欲综合网中文字幕| 天堂а√中文最新版在线| 成人污污污www网站免费| 亚洲人亚洲人成电影网站色| 天天躁日日躁狠狠躁欧美老妇小说 | 亚洲精品国产品国语原创| 18禁男女无遮挡啪啪网站| 欧美精品色婷婷五月综合| 猫咪www免费人成人入口| 婷婷五月综合激情中文字幕| 97se亚洲精品一区二区| 亚洲一区二区三区小说| 国产肉体xxxx裸体137大胆|