在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Dog Endoplasmin (HSP90B1), partial

Recombinant Dog Endoplasmin (HSP90B1), partial

  • 中文名稱：
    熟悉的犬HSP90B1重組蛋白
  • 貨號：
    CSB-YP010814DO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    熟悉的犬HSP90B1重組蛋白
  • 貨號：
    CSB-EP010814DO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    熟悉的犬HSP90B1重組蛋白
  • 貨號：
    CSB-EP010814DO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    熟悉的犬HSP90B1重組蛋白
  • 貨號：
    CSB-BP010814DO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    熟悉的犬HSP90B1重組蛋白
  • 貨號：
    CSB-MP010814DO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    HSP90B1; GRP94; TRA1Endoplasmin; 94 kDa glucose-regulated protein; GRP-94; Heat shock protein 90 kDa beta member 1
  • 種屬：
    Canis familiaris (Dog) (Canis lupus familiaris)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10.
  • 基因功能參考文獻：
    1. Folding and domain interactions of three orthologs of Hsp90 have been reported. PMID: 29276035
    2. These findings suggest that Grp94 might act as a potential biomarker for prognosis of canine mammary tumors and monitoring its therapy. PMID: 28801701
    3. The results provide structural insight into the ATP-dependent client maturation process of GRP94. PMID: 28930677
    4. Increased HSP90 expression in canine PCs suggests the involvement of this molecule in carcinogenesis and tumour progression, supporting HSP90 as a potential target for therapeutic intervention. PMID: 24679854
    5. is a constitutively expressed molecular chaperone and plays an important role in the folding of client proteins with key regulatory roles in growth, survival, differentiation and metastasis. PMID: 24418710
    6. structural maturation of the client protein substrate, rather than ATP binding or hydrolysis, serves as the primary signal for dissociation of GRP94-client protein complexes PMID: 15236592
    7. Data report the 2.4 A crystal structure of GRP94 in complex with AMPPNP and ADP, and provide a structural explanation for GRP94's observed rate of ATP hydrolysis. PMID: 17936703
    8. expression of TLR2, but not TLR4, on synovial fluid macrophages strongly correlated with the level of gp96 in the synovial fluid PMID: 19342676
    9. The ATPase activity of GRP94 is essential for chaperone activity in vivo and the essential protein-binding domain of GRP94 is distinct from the N-terminal domain. PMID: 19553200

    顯示更多

    收起更多

  • 亞細胞定位：
    Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen. Melanosome.
  • 蛋白家族：
    Heat shock protein 90 family
  • 組織特異性：
    Detected in heart muscle (at protein level).
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲国产婷婷香蕉久久久久久| 久久久亚洲精品成人| 人与禽交videos欧美| 免费无码av片在线观看| 最新无码人妻在线不卡| 国产精品禁18久久久夂久| 狠狠躁天天躁中文字幕| 美女张开腿让人桶| 国产免费午夜福利在线播放11| 国产美女精品视频线免费播放软件| 国产露脸150部国语对白| 欧美大屁股xxxx高跟欧美黑人| 亚洲色一色噜一噜噜噜| 成人午夜福利免费体验区| 日日噜噜噜噜夜夜爽亚洲精品| 亚洲国产午夜精品理论片在线播放 | 亚洲国产成人超a在线播放| 国色天香社区在线视频 | 中文字幕在线影视| 国产亚洲精品久久久久婷婷瑜伽 | 日本少妇xxxx做受| 在线成人一区二区| 亚洲精品久久久久久动漫器材一区| 国产午夜片无码区在线观看爱情网 | 国产成年无码久久久久毛片| 国产精品久久久久久久久动漫| 四库影院永久国产精品| 午夜性爽视频男人的天堂| 蜜桃视频在线观看免费视频网站www | 人人爽人人爽人人片av免费| 2023国产精品一卡2卡三卡4卡| 午夜理理伦电影a片无码 | 少妇高潮太爽了在线视| 动漫精品视频一区二区三区| 天堂在线最新版资源www中文| 一本丁香综合久久久久不卡网站 | 国产人在线成免费视频| 精品丰满人妻无套内射| 少妇又爽又刺激视频| 蜜桃传媒av免费观看麻豆| 天堂а√在线中文在线最新版|