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  4. Recombinant Danio rerio POC1 centriolar protein homolog B (poc1b)

Recombinant Danio rerio POC1 centriolar protein homolog B (poc1b)

  • 中文名稱：
    斑馬魚poc1b重組蛋白
  • 貨號：
    CSB-YP026040DIL
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    斑馬魚poc1b重組蛋白
  • 貨號：
    CSB-EP026040DIL
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    斑馬魚poc1b重組蛋白
  • 貨號：
    CSB-EP026040DIL-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    斑馬魚poc1b重組蛋白
  • 貨號：
    CSB-BP026040DIL
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    斑馬魚poc1b重組蛋白
  • 貨號：
    CSB-MP026040DIL
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    poc1b
  • Uniprot No.：
  • 別名：
    poc1b; tuwd12; wdr51b; si:dkey-164B12.2; POC1 centriolar protein homolog B; WD repeat domain 51B
  • 種屬：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-490
  • 氨基酸序列
    MASVMEDPTL ERHFKGHKDV ISCADFNPNN KQLATGSCDK SLMIWNLAPK ARAFRFVGHT DVITGVNFAP SGSLVASSSR DQTVRLWTPS IKGESTVFKA HTASVRSVHF SRDGQRLVTA SDDKSVKVWG VERKKFLYSL NRHTNWVRCA RFSPDGRLIA SCGDDRTVRL WDTSSHQCIN IFTDYGGSAT FVDFNSSGTC IASSGADNTI KIWDIRTNKL IQHYKVHNAG VNCFSFHPSG NYLISGSSDS TIKILDLLEG RLIYTLHGHK GPVLTVTFSR DGDLFASGGA DSQVLMWKTN FDSLNYRELL SKHSKRVTPD PPPHLMDIYP RSHHRHHPQN GTVEINPVAD TQSTDPQVVE VGRVVFSTTD ARNYDGASSS RAQFTSGMDS GPFRTHTQAR EEEDENQEER FAGGMTASPA ERSGIPSSLT STLENIVQQL DILTQTVAVL EERLTLTEDK LRTCLDNQVL LMQQNQQLDR SDEESEGPPL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control.
  • 基因功能參考文獻：
    1. data suggest that poc1b is required for normal development and ciliogenesis of retinal photoreceptor sensory cilia and other cilia PMID: 26188096
    2. Poc1B knockdown causes ciliary defects & morphological phenotype consistent with ciliopathies; Poc1 provides link between assembly & stability of centrioles for ciliary-based motility in Tetrahymena & cilia formation & function in D rerio & humans PMID: 20008567
  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
  • 蛋白家族：
    WD repeat POC1 family
  • 數據庫鏈接：


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