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  4. Recombinant Danio rerio Histone-lysine N-methyltransferase SUV39H1-A (suv39h1a)

Recombinant Danio rerio Histone-lysine N-methyltransferase SUV39H1-A (suv39h1a)

  • 中文名稱：
    斑馬魚suv39h1a重組蛋白
  • 貨號：
    CSB-YP735303DIL
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    斑馬魚suv39h1a重組蛋白
  • 貨號：
    CSB-EP735303DIL
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    斑馬魚suv39h1a重組蛋白
  • 貨號：
    CSB-EP735303DIL-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    斑馬魚suv39h1a重組蛋白
  • 貨號：
    CSB-BP735303DIL
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    斑馬魚suv39h1a重組蛋白
  • 貨號：
    CSB-MP735303DIL
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    suv39h1a
  • Uniprot No.：
  • 別名：
    suv39h1a; suv39h1; si:dkey-16n15.2; zgc:101027; Histone-lysine N-methyltransferase SUV39H1-A; EC 2.1.1.-; Suppressor of variegation 3-9 homolog 1-A; Su(var)3-9 homolog 1-A
  • 種屬：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-411
  • 氨基酸序列
    MARDLKDCRVPCKLLLEDLQALCRRKKLVCKQLSVTKNNFNDYEVEYLCNYKKHKGREFF LVKWKGYEESENTWEPLKNLKCPILLHQFRKDMKAALLQANEPLDSASLSGPIISFLRQK ATQRIRLKKWEDLMNQTCWHKGRIFVSNEVDMDGPPKNFTYINENKLGKGVDMNAVIVGC ECEDCVSQPVDGCCPGLLKFRRAYNESRRVKVMPGVPIYECNSKCRCGPDCANRVVQRGI QYDLCIFKTDNGRGWGVRTLQRINKNSFVMEYLGEIITTDEAEQRGVLYDKQGVTYLFDL DYVDDVYTIDAAHYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIALFAKRGIKAGEEL TFDYKMTVDPVDAESTKMDLDFSRAGIEGSPIKRVHMECKCGVRNCRKYLF
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as regulation of organ-specific terminal differentiation during development.
  • 基因功能參考文獻：
    1. The identification of a histone H3 lysine 9 histone methyltransferase, SUV39H1, as a suppressor of embryonal rhabdomyosarcoma formation in zebrafish, is described. PMID: 23705022
  • 亞細(xì)胞定位：
    Nucleus. Chromosome, centromere.
  • 蛋白家族：
    Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, Suvar3-9 subfamily
  • 組織特異性：
    Expressed ubuitiously.
  • 數(shù)據(jù)庫鏈接：


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