在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Danio rerio Denticleless protein homolog (dtl), partial

Recombinant Danio rerio Denticleless protein homolog (dtl), partial

  • 中文名稱(chēng)：
    斑馬魚(yú)dtl重組蛋白
  • 貨號(hào)：
    CSB-YP725479DIL
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    斑馬魚(yú)dtl重組蛋白
  • 貨號(hào)：
    CSB-EP725479DIL
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    斑馬魚(yú)dtl重組蛋白
  • 貨號(hào)：
    CSB-EP725479DIL-B
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    斑馬魚(yú)dtl重組蛋白
  • 貨號(hào)：
    CSB-BP725479DIL
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    斑馬魚(yú)dtl重組蛋白
  • 貨號(hào)：
    CSB-MP725479DIL
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    dtl
  • Uniprot No.：
  • 別名：
    dtl; cdt2; si:dkey-18c8.4Denticleless protein homolog
  • 種屬：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), KMT5A and SDE2. CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. KMT5A degradation is also important for a proper regulation of mechanisms such as TGF-beta signaling, cell cycle progression, DNA repair and cell migration. Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation. In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis. May play a role in the regulation of the circadian clock.
  • 基因功能參考文獻(xiàn)：
    1. DTL promotes genomic stability through two distinct mechanisms. First, it is an essential component of the CUL4-DDB1 complex that controls CDT1 levels, thereby preventing rereplication. Second, it is required for the early G2/M checkpoint. PMID: 17085480
  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome.
  • 蛋白家族：
    WD repeat cdt2 family
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: dre:192314

    STRING: 7955.ENSDARP00000033992

    UniGene: Dr.3526



主站蜘蛛池模板： 亚洲人色婷婷成人网站在线观看 | 国产九九99久久99大香伊| 丁香五月亚洲综合深深爱| 国产成人av在线播放影院| 久久精品一区二区av999| 久久久久无码国产精品一区| 处破痛哭a√18成年片免费| 18禁亚洲深夜福利入口| 欧美成人性做爰77777| 国产精品人人做人人爽| 亚洲性无码av在线欣赏网| 亚洲国产欧美一区点击进入| 中文成人无码精品久久久动漫| 免费少妇荡乳情欲视频| 男女啪啪永久免费观看网站| 午夜性开放午夜性爽爽| 亚洲人成网站18禁止大| 久久丫精品系列| 午夜免费啪视频| 久久综合九色综合97婷婷| 午夜人性色福利无码视频在线观看| 欧洲人妻丰满av无码久久不卡| 少妇粉嫩小泬喷水视频| 国产嘿嘿嘿视频在线观看| 国产午夜福利不卡在线观看| 亚洲人成伊人成综合网久久久| 香港三日本8a三级少妇三级99 | 亚洲精品国产suv一区| 日韩精品中文字幕无码一区| 国厂精品114福利电影免费| 亚洲精品一区久久久久| 成熟丰满熟妇av无码区| 亚洲夜色噜噜av在线观看| 人妻丰满熟妇av无码区动漫| 久久综合久色欧美综合狠狠| 国模大尺度啪啪| 中日精品无码一本二本三本| 99精品人妻少妇一区二区| 妺妺窝人体色www在线小说| 色猫咪免费人成网站在线观看| 亚洲乱码伦小说区|