在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Crotalus durissus terrificus Crotoxin acid chain

Recombinant Crotalus durissus terrificus Crotoxin acid chain

  • 中文名稱：
    Recombinant Crotalus durissus terrificus Crotoxin acid chain
  • 貨號：
    CSB-YP357508DYD
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Crotalus durissus terrificus Crotoxin acid chain
  • 貨號：
    CSB-EP357508DYD
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Crotalus durissus terrificus Crotoxin acid chain
  • 貨號：
    CSB-EP357508DYD-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Crotalus durissus terrificus Crotoxin acid chain
  • 貨號：
    CSB-BP357508DYD
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Crotalus durissus terrificus Crotoxin acid chain
  • 貨號：
    CSB-MP357508DYD
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    Phospholipase A2 homolog crotoxin acid subunit CA; CTX subunit CA; Crotapotin) [Cleaved into: Crotoxin chain alpha CA1; CA2 and CA4; Crotoxin chain alpha CA3; Crotoxin chain beta CA2; CA3 and CA4; Crotoxin chain beta CA1; Crotoxin chain gamma; Analgesic peptide; Crotalphine)]
  • 種屬：
    Crotalus durissus terrificus (South American rattlesnake)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    38-78
  • 氨基酸序列
    SSY GCYCGAGGQG WPQDASDRCC FEHDCCYAKL TGCDPTTD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    CAalpha-CAbeta-CAgamma: The acidic subunit of crotoxin (CA) is a heterotrimer of three disulfide-linked chains generated by post-translational maturation of a PLA2-like precursor. CA has no PLA2 activity and is not neurotoxic by itself, but plays several important functions in the crotoxin complex by increasing the lethal potency of the uncomplexed CB subunit. It acts by physically occluding the hydrophobic interfacial binding surface (IBS) of CB. This effect decreases the adsorption of CB to phospholipid membranes, targeting the crotoxin complex to reach the specific presynaptic receptor (R48) at the neuromuscular junction. It also prevents the formation of the reactive CB dimer. Moreover, the CA subunit inhibits the catalytic activity by partially masking the catalytic site of CB and inhibits its anticoagulant activity.; Heterodimer CA-CB: Crotoxin is a potent presynaptic neurotoxin that possesses phospholipase A2 (PLA2) activity and exerts a lethal action by blocking neuromuscular transmission. It consists of a non-covalent association of a basic and weakly toxic PLA2 subunit (CBa2, CBb, CBc, or CBd), with a small acidic, non-enzymatic and non-toxic subunit (CA1, CA2, CA3 or CA4). The complex acts by binding to a specific 48-kDa protein (R48/CAPT) receptor located on presynaptic membranes, forming a transient ternary complex CA-CB-R48, followed by dissociation of the CA-CB complex and release of the CA subunit. At equilibrium, only the CB subunits remain associated with the specific crotoxin receptor. In addition to neurotoxicity, crotoxin has been found to exert myotoxicity, nephrotoxicity, and cardiovascular toxicity. Moreover, anti-inflammatory, immunomodulatory, anti-tumor and analgesic effects of crotoxin have also been reported.; found in the venom as a monomer and stabilized by one disulfide bond (Cys-131 and Cys-138). This peptide induces potent antinociceptive effects in acute and chronic pain models. This effect is mediated by the release of peripheral dynorphin A, an endogenous agonist of kappa-opioid receptors, and this release is dependent on cannabinoid receptor CB2 activation.
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Phospholipase A2 family, Group II subfamily, D49 sub-subfamily
  • 組織特異性：
    Expressed by the venom gland.


主站蜘蛛池模板： 色橹橹欧美在线观看视频高清| 欧美伦费免费全部午夜最新| 2021自拍偷在线精品自拍偷| 又色又爽又黄18禁美女裸身无遮挡 | 性色av一二三天美传媒| 蜜桃av噜噜一区二区三区| 欧美激情综合五月色丁香| 成人精品一区日本无码网站| 丁香五月亚洲中文字幕| 久久大香国产成人av| 乱色熟女综合一区二区三区| _97夜夜澡人人爽人人喊_欧美| 精品亚洲成a人片在线观看| 欧美性猛交内射兽交老熟妇| 内射老妇bbwx0c0ck| 免费无码久久成人影片| 欧美日本特级婬片视频| 漂亮人妻被中出中文字幕| 久久精品国产69国产精品亚洲| 午夜精品久久久久久久99热| 久久这里只精品国产免费9| 国产女人天天春夜夜春| 亚洲精品乱码久久久久久按摩| 美女网站免费观看视频| 免费无码一区二区三区蜜桃大 | 久久www色情成人免费| 一区二区三区毛aaaa片特级| 无码乱码av天堂一区二区| 人人妻人人做人人爽| 神马午夜福利不卡片在线| 亲子乱子伦xxxx视频| 搡老熟女老女人一区二区| 国产精品白浆在线观看免费| 国产男生夜间福利免费网站| 亚洲成a人片在线观看无码专区| 精品一区二区三区东京热| 成人亚洲欧美久久久久| 日本丰满熟妇hd| 99re6在线视频精品免费| 中文字幕aav| 在线观看特色大片免费视频 |