在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Crotalus durissus terrificus Crotoxin acid chain

Recombinant Crotalus durissus terrificus Crotoxin acid chain

  • 中文名稱：
    Recombinant Crotalus durissus terrificus Crotoxin acid chain
  • 貨號：
    CSB-YP357508DYD
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Crotalus durissus terrificus Crotoxin acid chain
  • 貨號：
    CSB-EP357508DYD
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Crotalus durissus terrificus Crotoxin acid chain
  • 貨號：
    CSB-EP357508DYD-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Crotalus durissus terrificus Crotoxin acid chain
  • 貨號：
    CSB-BP357508DYD
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Crotalus durissus terrificus Crotoxin acid chain
  • 貨號：
    CSB-MP357508DYD
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    Phospholipase A2 homolog crotoxin acid subunit CA; CTX subunit CA; Crotapotin) [Cleaved into: Crotoxin chain alpha CA1; CA2 and CA4; Crotoxin chain alpha CA3; Crotoxin chain beta CA2; CA3 and CA4; Crotoxin chain beta CA1; Crotoxin chain gamma; Analgesic peptide; Crotalphine)]
  • 種屬：
    Crotalus durissus terrificus (South American rattlesnake)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    38-78
  • 氨基酸序列
    SSY GCYCGAGGQG WPQDASDRCC FEHDCCYAKL TGCDPTTD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    CAalpha-CAbeta-CAgamma: The acidic subunit of crotoxin (CA) is a heterotrimer of three disulfide-linked chains generated by post-translational maturation of a PLA2-like precursor. CA has no PLA2 activity and is not neurotoxic by itself, but plays several important functions in the crotoxin complex by increasing the lethal potency of the uncomplexed CB subunit. It acts by physically occluding the hydrophobic interfacial binding surface (IBS) of CB. This effect decreases the adsorption of CB to phospholipid membranes, targeting the crotoxin complex to reach the specific presynaptic receptor (R48) at the neuromuscular junction. It also prevents the formation of the reactive CB dimer. Moreover, the CA subunit inhibits the catalytic activity by partially masking the catalytic site of CB and inhibits its anticoagulant activity.; Heterodimer CA-CB: Crotoxin is a potent presynaptic neurotoxin that possesses phospholipase A2 (PLA2) activity and exerts a lethal action by blocking neuromuscular transmission. It consists of a non-covalent association of a basic and weakly toxic PLA2 subunit (CBa2, CBb, CBc, or CBd), with a small acidic, non-enzymatic and non-toxic subunit (CA1, CA2, CA3 or CA4). The complex acts by binding to a specific 48-kDa protein (R48/CAPT) receptor located on presynaptic membranes, forming a transient ternary complex CA-CB-R48, followed by dissociation of the CA-CB complex and release of the CA subunit. At equilibrium, only the CB subunits remain associated with the specific crotoxin receptor. In addition to neurotoxicity, crotoxin has been found to exert myotoxicity, nephrotoxicity, and cardiovascular toxicity. Moreover, anti-inflammatory, immunomodulatory, anti-tumor and analgesic effects of crotoxin have also been reported.; found in the venom as a monomer and stabilized by one disulfide bond (Cys-131 and Cys-138). This peptide induces potent antinociceptive effects in acute and chronic pain models. This effect is mediated by the release of peripheral dynorphin A, an endogenous agonist of kappa-opioid receptors, and this release is dependent on cannabinoid receptor CB2 activation.
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Phospholipase A2 family, Group II subfamily, D49 sub-subfamily
  • 組織特異性：
    Expressed by the venom gland.


主站蜘蛛池模板： 亚洲精品入口一区二区乱麻豆精品| 2018天天拍拍天天爽视频| 免费看国产成年无码av片| 天天综合色天天综合色hd| 国产午夜精品一区二区三区不卡| 中文字幕乱码人妻综合二区三区| 欧美xxxx黑人又粗又长精品| 婷婷色婷婷开心五月| 欧美激情一区二区成人| 亚洲 欧美 动漫 少妇 自拍| 亚洲欧美日韩一区二区| 朝鲜美女黑毛bbw| 3d动漫精品一区二区三区| 日韩精品无码中文字幕一区二区| 国产亚洲熟妇综合视频| 亚洲无碼网站观看| 成人亚洲性情网站www在线观看| 国产精品原创巨作av| 国内精品久久久久久久久电影网| 中国做爰国产精品视频| 日产精品久久久久久久| 成年无码av片| 99精品无码一区二区| 亚洲婷婷开心色四房播播| 囯产精品一区二区三区线| 综合人妻久久一区二区精品| 无码熟妇人妻av在线影片最多| 女m羞辱调教视频网站| 国产成人av在线一区二区三区| 亚洲男同gv在线观看| 久久国产36精品色熟妇| 欧美成妇人吹潮在线播放| 天堂网在线www中文| 欧美大屁股熟妇bbbbbb| 日本一二三区视频在线| 亚洲午夜无码久久yy6080| 日韩精品无码不卡无码| 熟女内射v888av| 99re6热在线精品视频观看| 亚洲精品无码成人片| 久久精品成人亚洲另类欧美 |