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  4. Recombinant Coturnix coturnix japonica Vascular endothelial growth factor receptor 2 (KDR), partial

Recombinant Coturnix coturnix japonica Vascular endothelial growth factor receptor 2 (KDR), partial

  • 中文名稱：
    Recombinant Coturnix coturnix japonica Vascular endothelial growth factor receptor 2(KDR) ,partial
  • 貨號：
    CSB-YP346773DXJ
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Coturnix coturnix japonica Vascular endothelial growth factor receptor 2(KDR) ,partial
  • 貨號：
    CSB-EP346773DXJ
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Coturnix coturnix japonica Vascular endothelial growth factor receptor 2(KDR) ,partial
  • 貨號：
    CSB-EP346773DXJ-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Coturnix coturnix japonica Vascular endothelial growth factor receptor 2(KDR) ,partial
  • 貨號：
    CSB-BP346773DXJ
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Coturnix coturnix japonica Vascular endothelial growth factor receptor 2(KDR) ,partial
  • 貨號：
    CSB-MP346773DXJ
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    KDR; EK1; FLK-1; Vascular endothelial growth factor receptor 2; VEGFR-2; EC 2.7.10.1; Endothelial kinase receptor EK1; Quek 1; Quek1
  • 種屬：
    Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and/or VEGFD and plays an essential role in the regulation of angiogenesis and vascular development. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Binding of vascular growth factors leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, reorganization of the actin cytoskeleton and activation of PTK2/FAK1. Required for VEGFA-mediated induction of NOS2 and NOS3, leading to the production of the signaling molecule nitric oxide (NO) by endothelial cells.
  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle. Early endosome. Cell junction. Endoplasmic reticulum.
  • 蛋白家族：
    Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily
  • 組織特異性：
    In all endothelial tissues during onset of vascularization. In later development, present in lung, heart, intestine and skin.


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