在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Colobus guereza Serine/threonine-protein kinase 4 (STK4)

  • 中文名稱:
    Recombinant Colobus guereza Serine/threonine-protein kinase 4(STK4)
  • 貨號:
    CSB-YP022855DVH
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Colobus guereza Serine/threonine-protein kinase 4(STK4)
  • 貨號:
    CSB-EP022855DVH
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Colobus guereza Serine/threonine-protein kinase 4(STK4)
  • 貨號:
    CSB-EP022855DVH-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Colobus guereza Serine/threonine-protein kinase 4(STK4)
  • 貨號:
    CSB-BP022855DVH
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Colobus guereza Serine/threonine-protein kinase 4(STK4)
  • 貨號:
    CSB-MP022855DVH
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    STK4; Serine/threonine-protein kinase 4; EC 2.7.11.1) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit; MST1/N); Serine/threonine-protein kinase 4 18kDa subunit; MST1/C)]
  • 種屬:
    Colobus guereza (Black-and-white colobus monkey)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-487
  • 氨基酸序列
    METVQLRNPP RRQLKKLDED SLTKQPEEVF DVLEKLGEGS YGSVYKAIHK ETGQIVAIKQ VPVESDLQEI IKEISIMQQC DSPHVVKYYG SYFKNTDLWI VMEYCGAGSV SDIIRLRNKT LTEDEIATVL QSTLKGLEYL HFMRKIHRDI KAGNILLNTE GHAKLADFGV AGQLTDTMAK RNTVIGTPFW MAPEVIQEIG YNCVADIWSL GITAIEMAEG KPPYADIHPM RAIFMIPTNP PPTFRKPELW SDNFTDFVKQ CLVKSPEQRA TATQLLQHPF VKSAKGVSIL RDLINEAMDV KLKRQESQQR EVDQDDEENS EEDEMDSGTM VRAVGDEMGT VRVASTMTDG ANTMIEHDDT LPSQLGTMVI NTEDEEEEGT MKRRDETMQP AKPSFLEYFE QKEKENQINS FGKSVPGPLK NSSDWKIPQD GDYEFLKSWT VEDLQKRLLA LDPMMEQEIE EIRQKYQSKR QPILDAIEAK KRRQQNF
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation. Phosphorylates 'Ser-14' of histone H2B (H2BS14ph) during apoptosis. Phosphorylates FOXO3 upon oxidative stress, which results in its nuclear translocation and cell death initiation. Phosphorylates MOBKL1A, MOBKL1B and RASSF2. Phosphorylates TNNI3 (cardiac Tn-I) and alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T). Phosphorylates FOXO1 on 'Ser-212' and regulates its activation and stimulates transcription of PMAIP1 in a FOXO1-dependent manner. Phosphorylates SIRT1 and inhibits SIRT1-mediated p53/TP53 deacetylation, thereby promoting p53/TP53 dependent transcription and apoptosis upon DNA damage. Acts as an inhibitor of PKB/AKT1. Phosphorylates AR on 'Ser-650' and suppresses its activity by intersecting with PKB/AKT1 signaling and antagonizing formation of AR-chromatin complexes.
  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily


主站蜘蛛池模板: 精品国产青草久久久久福利| 久久天天躁夜夜躁狠狠躁| 黄瓜视频在线观看网址| 成年无码av片| 国产内射999视频一区| 深夜国产一区二区三区在线看 | 高清性欧美暴力猛交| 精品免费国偷自产在线视频| 国产精品毛片大码女人| 日日躁夜夜躁白天躁晚上| 国产精品久久综合免费| 区二区三区国产精华液区别大吗| 国产精品又黄又爽又色无遮挡| 国产精品一区二区久久| 天天爽夜夜爽人人爽从早干到睌| 好紧好爽好深再快点av在线| 日本公妇乱偷中文字幕| 男人的天堂av网站| 国产精品sm捆绑调教视频| 国产成人精品自在线拍| 中文字幕亚洲无线码在线一区| 国产精品制服| 久久99亚洲精品久久久久| 亚洲人ⅴsaⅴ国产精品| 国产产区一二三产区区别在线 | 怡红院av亚洲一区二区三区h| 久久99精品久久久久久秒播| 99热成人精品热久久6网站| 色哟哟最新在线观看入口| 欧美成a人片在线观看久| 精品人妻无码区在线视频| 高清av熟女一区| 日本黄网站免费| 97久久精品无码一区二区天美| 99热这里只就有精品22| 乱色国内精品视频在线| 国产真人性做爰久久网站| 日韩精品中文字幕无码一区| 欧美人与动牲交app视频| 国产3p露脸普通话对白| 国产av综合影院|