在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Chicken Transcription factor SOX-9 (SOX9)

Recombinant Chicken Transcription factor SOX-9 (SOX9)

  • 中文名稱：
    雞SOX9重組蛋白
  • 貨號：
    CSB-YP022437CH
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    雞SOX9重組蛋白
  • 貨號：
    CSB-EP022437CH
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    雞SOX9重組蛋白
  • 貨號：
    CSB-EP022437CH-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    雞SOX9重組蛋白
  • 貨號：
    CSB-BP022437CH
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    雞SOX9重組蛋白
  • 貨號：
    CSB-MP022437CH
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    SOX9; Transcription factor SOX-9
  • 種屬：
    Gallus gallus (Chicken)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-494
  • 氨基酸序列
    MNLLDPFMKM TEEQDKGLSG APSPTMSDDS AGSPCPSGSG SDTENTRPPQ ENTFPKGDPD LKKESDEDKF PVCIREAVSQ VLKGYDWTLV PMPVRVNGSS KNKPHVKRPM NAFMVWAQAA RRKLADQYPH LHNAELSKTL GKLWRLLNES EKRPFVEEAE RLRVQHKKDH PDYKYQPRRR KTVKNGQSEQ EEGSEQTHIS PNAIFKALQA DSPQSSSSIS EVHSPGEHSG QSQGPPTPPT TPKTDAQQPG KQDLKREGPL AEGGRQPPHI DFRDVDIGEL SSDVISNIET FDVNEFDQYL PPNGHPGVPA THGQVTTYSG TYGISSSASS PAGAGHAWMA KQQPQPPQPP AQPPAQHTLP STEREQGPAQ QRPHIKTEQL SPSHNSEQQQ HPEQQQQQQQ QLGYGSFNLQ HYGFSYPPIT RSEYDYTEHQ NSGSYYSHAA GQSGSLYSTF TYMNPTQRPM YTPIADTSGV PTIPQTHSPQ QHWEQPVYTQ LTRP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcription factor that plays a key role in chondrocytes differentiation and skeletal development. Specifically binds the 5'-ACAAAG-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including COL2A1. Plays a central role in successive steps of chondrocyte differentiation. Absolutely required for precartilaginous condensation, the first step in chondrogenesis during which skeletal progenitors differentiate into prechondrocytes. Together with SOX5 and SOX6, required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes, the second step in chondrogenesis. Later, required to direct hypertrophic maturation and block osteoblast differentiation of growth plate chondrocytes: maintains chondrocyte columnar proliferation, delays prehypertrophy and then prevents osteoblastic differentiation of chondrocytes. Also required for chondrocyte hypertrophy, both indirectly, by keeping the lineage fate of chondrocytes, and directly, by remaining present in upper hypertrophic cells. Low lipid levels are the main nutritional determinant for chondrogenic commitment of skeletal progenitor cells: when lipids levels are low, FOXO transcription factors promote expression of SOX9, which induces chondrogenic commitment and suppresses fatty acid oxidation. In addition to cartilage development, also acts as a regulator of proliferation and differentiation in epithelial stem/progenitor cells. In response to bone morphogenetic protein stimulus, phosphorylation is induced and then sumoylation, allowing cooperation with SNAI2 to trigger neural crest delamination.
  • 基因功能參考文獻：
    1. Avian digits may represent an evolutionary specialization of digit development consequence of a posterior polarization of signals responsible for limb outgrowth. In contrast, the pentadactyl autopod of mouse and turtle embryos may result from the uniform expansion (like opening a fan) of the signals that coordinate proliferation and differentiation of the skeletal progenitors. PMID: 28386540
    2. Mechanical stimulation enhances nuclear signals of the transcription factors Sox9 and CREB in a PKA and PP2A-dependent manner PMID: 24333667
    3. The results suggest that ETS1 and SOX9 may act as pan-neural crest regulators of the migratory cranial neural crest PMID: 24389048
    4. data suggest a model in which extracellular signals initiate phosphorylation of Sox9 and its cooperation with Snail2 to induce NCC delamination PMID: 23382206
    5. Sox9 mediates the direct conversion of tenocytes to chondrocytes through an intermediate state in which both differentiation programs are active. Sox9 is expressed in cartilage but is undetectable in limb tendons that express Scleraxis and Tenomodulin. PMID: 22510437
    6. NFIA is a transcription factor that plays a crucial role in the onset of gliogenesis; we found that its induction is regulated by the transcription factor Sox9 and that this relationship mediates the initiation of gliogenesis PMID: 22500632
    7. model whereby Sox and Nfi proteins bind to conserved Matn1 proximal elements and functionally interact with each other to finely tune gene expression in specific zones of the cartilage growth plate PMID: 21173167
    8. Results suggest that SOX9 is necessary and sufficient to specify pyloric sphincter epithelial properties. PMID: 15240557
    9. Data suggest that Sox9 and Nkx2.5 are regulated independently by bone morphogenetic protein signaling, and act coordinately to specify the pyloric sphincter. PMID: 15733673
    10. PD098059 attenuated the depletion of cartilage matrix as well as decreased the expression and phosphorylation of Sox9 in cultures treated with H(2)O(2) or cyclosporine. PMID: 15777799
    11. Results demonstrate that RhoA-mediated modulation of actin polymerization regulates the ability of Sox9 to both activate chondrocyte-specific markers and maintain its own expression in chondrocytes via a positive feedback loop. PMID: 19470758

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 數據庫鏈接：


主站蜘蛛池模板： 欧美一区二区三区成人片在线| 成人无遮挡裸免费视频在线观看 | 亚洲国产精品特色大片观看完整版| 四虎影视88aa久久人妻| 俺去啦俺来也五月天| 中文字幕精品一二三四五六七八| 亚洲精品自在在线观看| 亚洲欧美日韩国产综合一区二区| 国产精品亚洲玖玖玖在线观看| av制服丝袜白丝国产网站| 亚洲一区二区三区丝袜| 亚洲欧美日韩综合在线一| 精品日韩亚洲欧美高清a| 一本色道久久99一综合| 77777亚洲午夜久久多人| 国产99在线 | 免费| 久久国产福利播放| 精品亚洲国产成人av| 欧美激情一区二区三区| 国语对白做受xxxxx在| 国产无吗一区二区三区在线欢| 美女视频黄a视频全免费| 国产成人无码va在线观看| 在线观看无码av网站永久免费 | 亚洲色偷偷色噜噜狠狠99网| 五月丁香六月激情综合在线视频| 色综合亚洲一区二区小说性色aⅴ| 国产精品无码无片在线观看| 无码专区人妻系列日韩精品| 人人揉揉揉香蕉大免费| 波多野结衣办公室33分钟| 免费萌白酱国产一区二区三区| 国产精品自在自线视频| 天堂av成年av影视| 午夜精品久久久久久久无码 | 日本真人做爰免费的视频| 日韩av毛片无码免费| 性xxxx欧美老妇胖老太性多毛| 国产蜜臀av在线一区尤物| 波多野结衣爽到高潮大喷| 波多野结衣免费一区视频|