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  4. Recombinant Chicken Interferon regulatory factor 3 (IRF3)

Recombinant Chicken Interferon regulatory factor 3 (IRF3)

  • 中文名稱：
    雞IRF3重組蛋白
  • 貨號：
    CSB-YP011818CH
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    雞IRF3重組蛋白
  • 貨號：
    CSB-EP011818CH
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    雞IRF3重組蛋白
  • 貨號：
    CSB-EP011818CH-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    雞IRF3重組蛋白
  • 貨號：
    CSB-BP011818CH
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    雞IRF3重組蛋白
  • 貨號：
    CSB-MP011818CH
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    IRF3Interferon regulatory factor 3; IRF-3
  • 種屬：
    Gallus gallus (Chicken)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-491
  • 氨基酸序列
    MAALDSEGDA QKLRFGPWLL NAVSSGLYRG LCWIDPDRRI FRIPWKHNAR KDVTSSDVEI FKAWAKASGR YEGNAEDPAK WKTNFRCALR STHMFMLLED RSKCNDDPHK VYAVASGVPN DRGSGGPVAG ALQQQPQLLL NHHDLALENT PTDSTEGVAA AALTQVDLDL LQSVLQHCNI SALGSQPTLW AHTGDALPED ALLLPGQDGC LPGPQFQDWR QLEEPLLLGN QPLTGGGCGQ DGAGALPVSE ECAIPAPSPA EELLFQSANP APPPPAGDIG GLPPLLDITI YYRGKMVYQE QVDDSRCVLA YQPLDPAVAE QRLVLFPSPA SLPDPRQRRY TEDLLEVAGL RLEQRAGQLL ATRLKKCKVF WALSQQLEGG EPPLNLLHRD QETTIFDFRV FCTELRDFRD SRRERSPDFT IFLCFGQCFS STKPKESKLI LVKLVPQFCE YWYEQVQRGG ASSLNSGNVS LQLSDSFNLF ELIEQYHMQT D
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. May activate transcription by complex formation with other transcriptional factors, possibly members of the STAT family. Binds specifically to the IFN-stimulated response element (ISRE) but not to the IRF-1 binding site PRD-I.
  • 基因功能參考文獻：
    1. chTBK1 may be an important immunoregulator for IRF3 and IFNbeta induction in response to viral stimulation in chicken. PMID: 28493975
    2. IRF7 may have conserved functional activity in the avian antiviral response, and plays a crucial role in type I IFN regulation. PMID: 26186542
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    IRF family
  • 組織特異性：
    Widely expressed with higher expression in lung, spleen and intestine.
  • 數據庫鏈接：


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