在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Chicken Interferon gamma (IFNG)

In Stock
  • 中文名稱:
    雞IFNG重組蛋白
  • 貨號:
    CSB-EP011050CH
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    IFNG; Interferon gamma; IFN-gamma
  • 種屬:
    Gallus gallus (Chicken)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    43.7kDa
  • 表達區域:
    20-164aa
  • 氨基酸序列
    HTASSLNLVQLQDDIDKLKADFNSSHSDVADGGPIIVEKLKNWTERNEKRIILSQIVSMYLEMLENTDKSKPHIKHISEELYTLKNNLPDGVKKVKDIMDLAKLPMNDLRIQRKAANELFSILQKLVDPPSFKRKRSQSQRRCNC
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產品描述:

    The Recombinant Chicken IFNG protein is a protein encoded by recombinant DNA that was cloned in an expression vector that supported the expression of IFNG gene. This recombinant IFNG protein was expressed in the host. The expression region is 20-164aa of the Chicken IFNG. In the production, the expression vector contains N-terminal GST tag. Every production step was performed with a strict QC system. The purity of this protein is 90%+ determined by SDS-PAGE.

    interferon-gamma/Interferon γ coded by the IFNG gene is among the common cytokines known to affect immune related disorders. Blockade of PD1/PD-L1 activates T cells accompanied by interferon- gamma (IFN-g) secretion, which has been proposed to mediate both pro- and anti-tumoral activities. IFN-g mediates adaptive resistance through PD-L1 dependent and independent mechanisms, which is becoming a key issue to broaden cancer immunotherapy. Other research demonstrates that liver type 1 innate lymphoid cells develop locally via an interferon-γ–dependent loop. Specifically, deficiency in the gene encoding interferon-γ or one of its receptors (Ifngr1) selectively reduced the frequency and number of ILC1s and not cNK cells in the liver. Delivery of a plasmid containing the interferon-γ (IFN-γ) cDNA to IFN-g-deficient mice via hydrodynamic tail-vein injection selectively increased the frequency and number of liver’s ILC1s but not of liver cNK cells. Moreover, IFN-γ signaling promoted the expansion and differentiation of LSM cells but not of ILC1s, supporting a model in which IFN-γ acts on these local progenitors to promote liver ILC1 development. The findings advance researchers’ knowledge of the importance of extramedullary hematopoiesis to cells of lymphoid origin.

  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
  • 基因功能參考文獻:
    1. Knockdown of IFN-gamma did not seem to fully abrogate vaccine-induced protection against Marek's disease in chickens. PMID: 25673902
    2. Vitiligo in Smyth line chickens appears to be a Th1-polarized autoimmune disease, whereby IFN-gamma expression is strongly associated with parallel increases in IL-10 and IL-21, particularly during the early and active stages of vitiligo. PMID: 22113479
    3. The dose-response effects of supplemental dietary chormium on interferon-gamma expression in response to Newcastle disease virus vaccine in broiler chickens is reported. PMID: 17888472
    4. The pivotal role of chicken interferon-gamma in the pathogenesis and immunosuppression of infectious bursal disease virus infection in in vivo, ex vivo and in vitro experiments are reported. PMID: 17899460
    5. that in vitro stimulation with IBV resulted in ChIFN-gamma production in splenocytes of both infected birds and uninfected birds PMID: 19070879

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Type II (or gamma) interferon family
  • 數據庫鏈接:


主站蜘蛛池模板: 少妇高潮大叫好爽| 国产精品国产三级欧美二区| 华人在线亚洲欧美精品| 国产成人午夜福利电影在线播放| 国产无人区码一码二码三mba | 美乳丰满人妻无码视频| 国产三级视频在线观看视| 麻豆md0077饥渴少妇| 亚洲妓女综合网99| 极品人妻被黑人中出种子| 蜜芽av无码精品国产午夜| 丰满人妻熟妇乱又仑精品| 亚洲综合一区二区三区无码 | 久久久99无码一区| 国产成人精品av| 亚洲国产成人一区二区精品区| 亚欧无线一线二线三线区别| 久久三级中文欧大战字幕| 亚洲男人的天堂www| 嫩草av久久伊人妇女超级a| 爱性久久久久久久久| 欧洲女人牲交性开放视频| 中文字幕av无码免费久久| 99在线在线视频观看| (无码视频)在线观看| 亚洲成av大片大片在线播放| 国产av一区二区精品久久| 国产欧美久久一区二区| 精品国产麻豆免费人成网站| 国产在线拍揄自揄视频导航| 欧洲精品一线二线三线区别| 新国产三级视频在线播放| 国产拍拍拍无码视频免费| 又爽又黄又无遮挡网站| 欲香欲色天天综合和网| 亚洲妓女综合网99| 日本牲交大片无遮挡| 国产精品人妻久久久久| 中文久久乱码一区二区| 特级a做爰全过程片| 一边摸一边叫床一边爽av|