在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Chicken B-cell lymphoma 6 protein homolog (BCL6), partial

  • 中文名稱:
    Recombinant Chicken B-cell lymphoma 6 protein homolog(BCL6) ,partial
  • 貨號:
    CSB-YP736607CH
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Chicken B-cell lymphoma 6 protein homolog(BCL6) ,partial
  • 貨號:
    CSB-EP736607CH
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Chicken B-cell lymphoma 6 protein homolog(BCL6) ,partial
  • 貨號:
    CSB-EP736607CH-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Chicken B-cell lymphoma 6 protein homolog(BCL6) ,partial
  • 貨號:
    CSB-BP736607CH
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Chicken B-cell lymphoma 6 protein homolog(BCL6) ,partial
  • 貨號:
    CSB-MP736607CH
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    BCL6; RCJMB04_3d20B-cell lymphoma 6 protein homolog
  • 種屬:
    Gallus gallus (Chicken)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. Forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Represses its target genes by binding directly to the DNA sequence 5'-TTCCTAGAA-3' (BCL6-binding site) or indirectly by repressing the transcriptional activity of transcription factors. In GC B-cells, represses genes that function in differentiation, inflammation, apoptosis and cell cycle control, also autoregulates its transcriptional expression and up-regulates, indirectly, the expression of some genes important for GC reactions, such as AICDA, through the repression of microRNAs expression. An important function is to allow GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. In follicular helper CD4(+) T-cells (T(FH) cells), promotes the expression of T(FH)-related genes but inhibits the differentiation of T(H)1, T(H)2 and T(H)17 cells. Also required for the establishment and maintenance of immunological memory for both T- and B-cells. Suppresses macrophage proliferation through competition with STAT5 for STAT-binding motifs binding on certain target genes, such as CCL2 and CCND2. In response to genotoxic stress, controls cell cycle arrest in GC B-cells in both p53/TP53-dependedent and -independent manners. Besides, also controls neurogenesis through the alteration of the composition of NOTCH-dependent transcriptional complexes at selective NOTCH targets, such as HES5, including the recruitment of the deacetylase SIRT1 and resulting in an epigenetic silencing leading to neuronal differentiation.
  • 基因功能參考文獻:
    1. Findings reveal a complex regulatory network in which Bcl6 acts as a key element dictating the transition of DT40 B cells to plasma cells. PMID: 21674482
  • 亞細胞定位:
    Nucleus.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 亚洲一卡2卡三卡4卡国色天香 | 亚洲综合色自拍一区| 成人免费b2b网站大全在线| 五月综合缴情婷婷六月| 丰满少妇被猛烈进入试看| 国产精品一品二区三区的使用体验| 国产亚洲欧美日韩夜色凹凸成人 | 国内精品久久久人妻中文字幕| 人妻久久久精品99系列2021| 久久天天躁狠狠躁夜夜2o2o| 男女下面进入的视频免费午夜| 国产欧美综合一区二区三区| 国产一区丝袜在线播放| 国产色情又大又粗又黄的电影| 免费无遮挡无码永久视频 | 中文字幕+乱码+中文字幕一区| 女人夜夜春精品a片| 女人与拘性猛交视频| 中文字幕久久久久人妻中出| 伊人精品无码av一区二区三区| 粉嫩av国产一区二区三区| 美女啪啪网站又黄又免费| 国产午夜片无码区在线观看爱情网 | 色综合久久久无码中文字幕波多| 天天弄天天模| 四虎影视88aa久久人妻| 久九九久视频精品免费| 无套内谢孕妇毛片免费看看| 好紧好爽好湿别拔出来视频男男| 狠狠狠色丁香综合婷婷久久| 免费的污污的网站在线观看| 尤物永久网站| 国产亚洲综合网曝门系列| 日本三级带日本三级带黄| 成人免费毛片aaaaaa片| 人妻无码中文字幕| 日本xxxx丰满老妇| 人人超碰人人爱超碰国产| 夜夜爽一区二区三区精品| 国产成 人 综合 亚洲网站| 伊人久久大香线蕉无码|