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  4. Recombinant Chaetomium globosum Probable tRNA threonylcarbamoyladenosine biosynthesis protein KAE1 (KAE1)

Recombinant Chaetomium globosum Probable tRNA threonylcarbamoyladenosine biosynthesis protein KAE1 (KAE1)

  • 中文名稱：
    Recombinant Chaetomium globosum Probable tRNA threonylcarbamoyladenosine biosynthesis protein KAE1(KAE1)
  • 貨號：
    CSB-YP643143CHI
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Chaetomium globosum Probable tRNA threonylcarbamoyladenosine biosynthesis protein KAE1(KAE1)
  • 貨號：
    CSB-EP643143CHI
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Chaetomium globosum Probable tRNA threonylcarbamoyladenosine biosynthesis protein KAE1(KAE1)
  • 貨號：
    CSB-EP643143CHI-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Chaetomium globosum Probable tRNA threonylcarbamoyladenosine biosynthesis protein KAE1(KAE1)
  • 貨號：
    CSB-BP643143CHI
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Chaetomium globosum Probable tRNA threonylcarbamoyladenosine biosynthesis protein KAE1(KAE1)
  • 貨號：
    CSB-MP643143CHI
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    KAE1
  • Uniprot No.：
  • 別名：
    KAE1; CHGG_07268; tRNA N6-adenosine threonylcarbamoyltransferase; EC 2.3.1.234; N6-L-threonylcarbamoyladenine synthase; t(6)A synthase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1; tRNA threonylcarbamoyladenosine biosynthesis protein KAE1
  • 種屬：
    Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-356
  • 氨基酸序列
    MGLDITQKKR RIALGCEGSA NKLGIGVILH EGDTSTVLSN VRHTFVSPAG TGFLPKDTAQ HHRAFFVRVA KQALSDAGIR IADIDCICYT RGPGMGGPLA SVAVAARTLA LLWGKELVGV NHCVGHIEMG RTITGADHPV VLYVSGGNTQ VIAYAEQRYR IFGETLDIAV GNCLDRFARA LNISNDPAPG YNIEVLARKG GRVLLDLPYA VKGMDCSFSG ILTRAEELAA QMKANEGKGT DGEPFTGADL CFSLQETVFA MLVEITERAM AHVGSNQVLI VGGVGCNERL QEMMGLMAAD RGGSVYATDE RFCIDNGIMI AHAGLLAYET GFRTPIEEST CTQRFRTDEV LVKWRK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    KAE1 / TsaD family
  • 數據庫鏈接：


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