在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein mono-ADP-ribosyltransferase PARP10 (PARP10), partial

In Stock
  • 中文名稱:
    人PARP10重組蛋白
  • 貨號(hào):
    CSB-EP709602HU1
  • 規(guī)格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    PARP10
  • Uniprot No.:
  • 別名:
    ADP-ribosyltransferase diphtheria toxin-like 10;ARTD10;Poly [ADP-ribose] polymerase 10;PARP-10
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    45.5 kDa
  • 表達(dá)區(qū)域:
    650-1025aa
  • 氨基酸序列
    LEEEAALQLALHRSLEPQGQVAEQEEAAALRQALTLSLLEQPPLEAEEPPDGGTDGKAQLVVHSAFEQDVEELDRALRAALEVHVQEETVGPWRRTLPAELRARLERCHGVSVALRGDCTILRGFGAHPARAARHLVALLAGPWDQSLAFPLAASGPTLAGQTLKGPWNNLERLAENTGEFQEVVRAFYDTLDAARSSIRVVRVERVSHPLLQQQYELYRERLLQRCERRPVEQVLYHGTTAPAVPDICAHGFNRSFCGRNATVYGKGVYFARRASLSVQDRYSPPNADGHKAVFVARVLTGDYGQGRRGLRAPPLRGPGHVLLRYDSAVDCICQPSIFVIFHDTQALPTHLITCEHVPRASPDDPSGLPGRSPDT
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate and aspartate residues on target proteins. In contrast to PARP1 and PARP2, it is not able to mediate poly-ADP-ribosylation. Catalyzes mono-ADP-ribosylation of GSK3B, leading to negatively regulate GSK3B kinase activity. Involved in translesion DNA synthesis in response to DNA damage via its interaction with PCNA.
  • 基因功能參考文獻(xiàn):
    1. PARP10 expression decreased upon fasting, a condition that is characterized by increases in mitochondrial biogenesis. Finally, lower PARP10 expression is associated with increased fatty acid oxidation PMID: 29293500
    2. ARTD10 plays roles in immunity, metabolism ,apoptosis and DNA damage repair. [review] PMID: 24878761
    3. PARP10 binding to PCNA is required for translesion DNA synthesis. PMID: 24695737
    4. study results show that the interaction between PARP10 and NS1 of H5N1 avian influenza virus can change cell cycle, and PARP10 can affect virus replication PMID: 22176891
    5. novel PARP enzyme involved in the control of cell proliferation PMID: 15674325
    6. Overexpression of PARP10 results in loss of cell viability, although down-expression by short hairpin RNA leads to delayed G1 progression and concomitant cell death. PMID: 16455663
    7. alternative catalytic mechanism for PARP10 compared to PARP1 in which the acidic target residue of the substrate functionally substitutes for the catalytic glutamate by using substrate-assisted catalysis to transfer ADP-ribose PMID: 18851833

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus, nucleolus. Cytoplasm.
  • 組織特異性:
    Highly expressed in spleen and thymus. Intermediate levels in liver, kidney, pancreas, prostate, testis, ovary, intestine, and leukocytes. Low expression in heart, brain, placenta, lung, skeletal muscle, and colon.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 25895

    OMIM: 609564

    KEGG: hsa:84875

    STRING: 9606.ENSP00000325618

    UniGene: Hs.348609



主站蜘蛛池模板: 中文字幕无线码一区二区 | 亚洲色爱图小说专区| 久久人人爽人人人人片| 日本丰满熟妇videossex一| 久久国产福利一区二区| 国产女厕所盗摄老师厕所嘘嘘| 国产人妻人伦精品1国产盗摄| 亚洲熟熟妇xxxx| 国产第一页浮力影院入口| 一区二区三区四区在线 | 欧洲| 伊人久久综合色| 老司机亚洲精品影院无码| 日韩精品无码一区二区忘忧草| 国产精品久久国产精麻豆99网站| 午夜亚洲福利在线老司机| 97久久香蕉国产线看观看| 蜜桃av久久久一区二区三区麻豆| 久久精品中文字幕第一页| 一区二区免费高清观看国产丝瓜| 成人av片无码免费网站| 欧洲亚洲国产成人综合色婷婷| 欧美精品无码久久久久久| 久在线观看福利视频| 国产亚洲日韩在线播放更多| 亚洲精品午夜无码电影网| 202丰满熟女妇大| 性人久久网av| 最近中文字幕免费mv在线视频| 97久久精品人人槡人妻人| 国产女主播喷水视频在线观看 | 亚洲色素色无码专区| 欧美一区二区三区成人久久片| 亚洲日韩va无码中文字幕| 国产无遮挡又黄又爽在线视频 | 国产精品福利视频导航| 亚洲精品一品区二品区三品区| 久久国产福利一区二区| 亚洲欧美日韩v在线观看不卡| 忍不住的亲子中文字幕| 少妇精油按摩av无码中字| 国产亚洲精品欧洲在线观看 |