在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Calloselasma rhodostoma Thrombin-like enzyme ancrod

In Stock
  • 中文名稱:
    Recombinant Calloselasma rhodostoma Thrombin-like enzyme ancrod
  • 貨號:
    CSB-YP338742CBG
  • 規格:
    ¥2616
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    N/A
  • Uniprot No.:
  • 別名:
    Thrombin-like enzyme ancrod; SVTLE; EC 3.4.21.74; Fibrinogen-clotting enzyme; Snake venom serine protease; SVSP; Venombin A
  • 種屬:
    Calloselasma rhodostoma (Malayan pit viper) (Agkistrodon rhodostoma)
  • 蛋白長度:
    Full Length
  • 來源:
    Yeast
  • 分子量:
    28.6kDa
  • 表達區域:
    1-234aa
  • 氨基酸序列
    VIGGDECNINEHRFLVAVYEGTNWTFICGGVLIHPEWVITAEHCARRRMNLVFGMHRKSEKFDDEQERYPKKRYFIRCNKTRTSWDEDIMLIRLNKPVNNSEHIAPLSLPSNPPIVGSDCRVMGWGSINRRIDVLSDEPRCANINLHNFTMCHGLFRKMPKKGRVLCAGDLRGRRDSCNSDSGGPLICNEELHGIVARGPNPCAQPNKPALYTSIYDYRDWVNNVIAGNATCSP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產品描述:

    The recombinant Calloselasma rhodostoma Thrombin-like enzyme ancrod (SVTLE) is a yeast-expressed (1-234aa) protein with N-terminal 6xHis tag. The purity is 90%+ measured by SDS-PAGE. The highly developed genetic system, ease of use, reduced time input, and costs have made Pichia Pastoris an attractive organism for the expression and production of recombinant proteins. So we choose the Yeast?system to express this recombinant Thrombin-like enzyme ancrod (SVTLE) protein, which is able to carry specifically designed plasmids, and the plasmid used consists of restriction sites that can be used to insert the gene sequence of interest. Transformation of yeasts with the plasmid produces the desired protein and can be appropriately scaled up.

    Ancrod is a thrombin-like enzyme that induces rapid defibrinogenation in humans by splitting fibrinopeptide A from fibrinogen. Ancord was developed for the treatment of ischaemic stroke and myocardial infarction as well as deep-vein thrombosis. In addition to reducing fibrinogen, ancord also lowers blood viscosity, suppresses erythrocyte aggregation, indirectly stimulates thrombolysis, and possibly leads to vasodilatation. It also possesses a weak anticoagulant activity at high dosages.

  • Datasheet & COA:
    Please contact us to get it.

產品評價

問答及客戶評論

 常見問題解答
Q:

I hope you are having a nice day. I was wondering if you have any data regarding the bioactivity of CSB-EP338742CBG.

A:
Very nice to receive your inquiry. The protein we provide is full-length which is very likely to be active in theory, but we haven't validated yet.

靶點詳情

  • 功能:
    Thrombin-like snake venom serine protease that acts as an anticoagulant. It cleaves fibrinogen (FGA) to split off the A-fibrinopeptides (A, AY and AP), but not the B-fibrinopeptide. The resulting fibrin polymers are imperfectly formed and much smaller in size (1 to 2 um long) than the fibrin polymers produced by the action of thrombin. These ancrod-induced microthrombi are friable, unstable, urea-soluble and have significantly degraded alpha chains. They do not cross-link to form thrombi. They are markedly susceptible to digestion by plasmin and are rapidly removed from circulation by either reticuloendothelial phagocytosis or normal fibrinolysis, or both. Anticoagulation through the removal of fibrinogen from the blood is rapid, occurring within hours following its administration. It does not activate plasminogen and does not degrade preformed, fully cross-linked thrombin fibrin. It also reduces the level of plasminogen activator inhibitor (PAI) and may stimulate the release of tissue plasminogen activator (PLAT) from the endothelium. The profibrinolytic effect of these 2 actions appears to be limited to local microthrombus degradation.
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Peptidase S1 family, Snake venom subfamily
  • 組織特異性:
    Expressed by the venom gland.


主站蜘蛛池模板: 欧美肥老太牲交| 国语国产精精品国产国语清晰对话| 韩国精品一区二区三区四区 | 丰满少妇大力进入| 亚洲 高清 成人 动漫| 亚洲乱码国产乱码精品精大量| 丁香婷婷无码不卡在线| 国产精品青草久久久久福利99| 国产成人无码a区视频在线观看| 国产精品久久久久久爽爽爽| 亚洲久热中文字幕在线| 伊人色综合网久久天天| 中文字幕亚洲欧美在线不卡 | 成人做爰高潮片免费视频| 884aa四虎影成人精品| 亚洲国产精品久久精品| 欧美性欧美巨大黑白大战| 真人做作爱视频| 久久国产精品2020免费| av无码精品一区二区三区四区| 男人一边吃奶一边做爰免费视频| 99视频精品国产免费观看| 2020久久超碰国产精品最新 | av综合网男人的天堂| 手机看片久久国产免费| 亚洲成a人片77777kkkk| 欧美村妇激情内射| 国产精品欧美成人| 日本熟妇人妻xxxx| 国产成人综合久久久久久| 久久精品国产男包| 国产午夜福利久久精品| 国产精品永久免费| 中文人妻熟妇乱又伦精品| 国产亚洲综合久久系列| 97精品人妻系列无码人妻| 日韩 国产 变态另类 欧美| 国产拍揄自揄免费观看| 久久久久国产精品嫩草影院 | 国产日韩在线时看高清视频 | 亚洲婷婷开心色四房播播|