在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Caenorhabditis elegans Protein glp-1 (glp-1), partial

Recombinant Caenorhabditis elegans Protein glp-1 (glp-1), partial

  • 中文名稱：
    秀麗隱桿線蟲glp-1重組蛋白
  • 貨號：
    CSB-YP319558CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲glp-1重組蛋白
  • 貨號：
    CSB-EP319558CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲glp-1重組蛋白
  • 貨號：
    CSB-EP319558CXY-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲glp-1重組蛋白
  • 貨號：
    CSB-BP319558CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲glp-1重組蛋白
  • 貨號：
    CSB-MP319558CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    glp-1
  • Uniprot No.：
  • 別名：
    glp-1; emb-33; F02A9.6Protein glp-1
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Essential signaling protein which has a major role in germline and embryonic development; involved in cell fate decisions that require cell-cell interactions. Probable membrane-bound receptor for putative ligands lag-2 and apx-1. Upon ligand activation, and releasing from the cell membrane, the glp-1/Notch intracellular domain (NICD) probably forms a transcriptional activator complex with lag-1 and lag-3 and regulates expression of various genes; targets in the germline include lst-1 and sygl-1. Involved in the specification of the cell fates of the blastomeres, ABa and ABp. Proper signaling by glp-1 induces ABa descendants to produce anterior pharyngeal cells, and ABp descendants to adopt a different fate. Contributes to the establishment of the dorsal-ventral axis in early embryos. Required in postmitotic neurons in order to maintain the developmentally arrested larval state known as dauer, probably in response to lag-2. Regulates germ cell mitotic proliferation probably by regulating MAP kinase phosphatase lip-1 expression. Required for oocyte growth control. Plays a negative role in lifespan.
  • 基因功能參考文獻(xiàn)：
    1. These results provide the first experimental evidence of an essential role for HSP90 in Notch signaling in development. PMID: 29507057
    2. The authors find that Notch-dependent active transcription sites occur in a probabilistic fashion and, unexpectedly, do so in a steep gradient across the stem cell pool. PMID: 27705743
    3. Zygotically expressed MOM-2 (Wnt) is responsible for two distinct cell-cell interactions as the MS blastomere produces one-third of the body wall muscles. Both the inhibitory and the activating interactions require precise spatiotemporal expression of zygotic MOM-2, which is dependent upon two distinct GLP-1 Notch signals. PMID: 28049659
    4. Study suggests that GLP-1 signaling is directly responsible for driving all stages of proliferation in the wild-type germline, and loss of its activity causes differentiation without intervening, distinctly regulated transit-amplifying divisions. PMID: 26158953
    5. glp-1(ar202), a temperature-sensitive gain-of-function C. elegans NOTCH mutant, was employed to delineate NOTCH-driven tumor responses to radiotherapy. PMID: 26120834
    6. regulatory element is highly conserved in the paralogous glp-1 genomic environment, suggesting redundant developmental and physiological roles for the two Notch paralogs in the C. elegans nervous system. PMID: 23305862
    7. POS-1 regulates glp-1 mRNA translation by blocking access of other RNA-binding proteins to a key regulatory sequence PMID: 23034181
    8. The functional defect in glp-1(Pro) mutants occurs prior to or at the level of ligand interaction. PMID: 12586701
    9. the balance between POS-1 and SPN-4 controls the translation of maternal glp-1 mRNA PMID: 12702662
    10. Results suggest that TBX-37 and TBX-38 play a key role in distinguishing the outcomes of two sequential Glp-1/Notch-mediated interactions. PMID: 15056620
    11. Data support a model in which GLP-1 function in MSP-dependent oocyte growth is separable from its role in the proliferation versus meiotic entry decision. PMID: 19502484

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein. Cell projection, axon.; [glp-1/Notch intracellular domain]: Nucleus.
  • 組織特異性：
    Expressed in the distal mitotic region of the germ line. May be absent from the gonadal distal tip cell (DTC).
  • 數(shù)據(jù)庫鏈接：

    KEGG: cel:CELE_F02A9.6

    STRING: 6239.F02A9.6

    UniGene: Cel.6196



主站蜘蛛池模板： 久久激情五月丁香伊人| 欧美三级不卡在线观看| 中文字幕人妻高清乱码| 欲色影视天天一区二区三区色香欲 | 精品无码专区亚洲| 亚洲精品乱码久久久久久久久久久久 | 无码中文字幕av免费放dvd| 久久久久久久性潮| 女人裸体做爰免费视频| 四虎影视在线影院在线观看| 国产成+人+综合+亚洲 欧美| 四虎影视在线永久免费观看| 久久午夜伦鲁片免费无码| 少妇性bbb搡bbb爽爽爽欧美| 日韩人妻熟女中文字幕a美景之屋 高h纯肉无码视频在线观看 | 久久99精品久久久久子伦 | 中字幕视频在线永久在线| 国产亚洲精品a久久777777| 插我一区二区在线观看| 国产在线 | 中文| 国产精品国产自线拍免费不卡 | 好了av四色综合无码| 成在线人免费视频一区二区| 国内精品久久久久精免费| 色综合欧美五月俺也去| 欧美真人做爰在线观看| 国产精品自产拍在线观看| 国产在线观看无码的免费网站 | 黑色丝袜脚足国产在线看| 在线人视频观看免费| 中国白嫩丰满人妻videos| 日本va欧美va欧美va精品| 国产成人免费爽爽爽视频| 亚洲龙腾成小说人网| 上海少妇高潮狂叫喷水了| аⅴ资源天堂资源库在线| 久久综合亚洲色hezyo国产| 女性自慰网站免费看ww| 深爱婷婷国产在线精品av| 亚洲va国产va天堂va久久| 亚洲欧美综合中文|