在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Caenorhabditis elegans Dauer larva development regulatory growth factor daf-7 (daf-7)

In Stock
  • 貨號:
    CSB-EP311270CXY
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    daf-7
  • Uniprot No.:
  • 種屬:
    Caenorhabditis elegans
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    18.1 kDa
  • 表達區域:
    235-350aa
  • 氨基酸序列
    SHAKPVCNAEAQSKGCCLYDLEIEFEKIGWDWIVAPPRYNAYMCRGDCHYNAHHFNLAETGHSKIMRAAHKVSNPEIGYCCHPTEYDYIKLIYVNRDGRVSIANVNGMIAKKCGCS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Under harsh environmental conditions, larvae enter a developmentally arrested state known as dauer; TGF-beta-like daf-7 acts to inhibit dauer larva formation and promote growth. May be a ligand to cell surface receptor daf-4. May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. Involved in sensitivity to CO2 levels. In AWC neurons, acts to promote expression of srsx-3, a member of the GPCR family.
  • 基因功能參考文獻:
    1. DAF-7 expression decreases as animals age during adulthood. Age-dependent diminished expression contributes to the reduced sensitivity of aging animals to the effects of dietary restriction. PMID: 28107363
    2. Using functional, fluorescently-tagged protein, we find that, in animals with mutant DAF-28/IGF, the wild-type DAF-7/TGF-beta is mislocalized to and accumulates in the proximal axon of the ASI neuron. Activation of two different branches of the unfolded protein response can modulate both the developmental phenotype and DAF-7 mislocalization in DAF-28(R37C) animals, but appear to act through divergent mechanisms PMID: 27926939
    3. GLR-1 protein and glr-1 transcription are increased in neurons of DAF-7 mutants. PMID: 26054666
    4. daf-7 has a role in larval development and specifically affects molting and excretory canal development PMID: 23526825
    5. We show that aggregation and bordering are genetically complex, with multiple contributing quantitative trait loci (QTLs), and refine one QTL to identify a new gene affecting the daf-7 pathway, the GABA receptor EXP-1. PMID: 23284308

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    TGF-beta family
  • 組織特異性:
    Expression in the chemosensory neurons.
  • 數據庫鏈接:

    KEGG: cel:CELE_B0412.2

    STRING: 6239.B0412.2

    UniGene: Cel.19630



主站蜘蛛池模板: 亚洲午夜性猛春交xxxx| 日日碰狠狠添天天爽无码| 极品少妇被啪到呻吟喷水| 国产精品久久婷婷六月丁香| 午夜三级a三级三点| 久久不见久久见免费影院国语| 精品无码国产av一区二区三区| 国产影片中文字幕| 成视频年人黄网站视频福利| 久久精品国产亚洲不av麻豆 | 国产99久久久国产无需播放器| 九九视频免费精品视频| 精品国产偷窥一区二区| 天堂mv在线mv免费mv香蕉| 大屁股国产白浆一二区| 国产鲁鲁视频在线观看| 999zyz玖玖资源站永久| 99久久精品国产成人综合 | 亚洲日韩乱码久久久久久| 99久久精品免费看国产一区二区| 四虎国产精品永久地址入口| 最近日本免费观看高清视频| 国产麻豆剧传媒精品av| 色综合 图片区 小说区| 美女露出奶头扒开尿口视频直播| 国产网红无码精品视频| 天堂国产一区二区三区| 大屁股熟女白浆一区二区| 亚洲成av人片在线观看无| 天码av无码一区二区三区四区| 国产真实自在自线免费精品| 麻豆国产成人av高清在线观看| 久久国产精品无码一区二区三区| 久久人妻无码中文字幕| 亚洲综合色在线观看一区| 久久久久久av无码免费网站| 国产精品永久免费视频| 亚洲日韩看片成人无码| 伊人久久大香线蕉av网| 欧美亚洲国产精品久久高清| 国产av一区二区三区无码野战|