在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Serum amyloid A protein (SAA1)

In Stock
  • 中文名稱:
    牛SAA1重組蛋白
  • 貨號:
    CSB-EP020656BO
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    SAA1; SAA; Serum amyloid A protein; SAA) [Cleaved into: Amyloid protein A; Amyloid fibril protein AA)]
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    30.1 kDa
  • 表達區域:
    19-130aa
  • 氨基酸序列
    QWMSFFGEAYEGAKDMWRAYSDMREANYKGADKYFHARGNYDAAQRGPGGAWAAKVISDARENIQRFTDPLFKGTTSGQGQEDSRADQAANEWGRSGKDPNHFRPAGLPDKY
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-SUMO-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產品描述:

    The expression of recombinant Bovine SAA1 protein includes the construction of the expression vector containing the recombinant DNA and the transformation of the expression vector into the E.coli, which provides a variety of macromolecules and components required for transcription and translation. The recombinant DNA was formed by fusing the N-terminal 6xHis-SUMO tag and C-terminal Myc tag sequence to the designated sequence encoding the 19-130aa of the Bovine SAA1 protein. This N-terminal 6xHis-tagged recombinant Bovine SAA1 protein is also characterized by high purity, >85%. Under SDS-PAGE condition, this recombinant SAA1 protein migrated to the band of about 33 kDa molecular weight.

    SAA1 protein is expressed primarily in the liver and circulates in low levels in the blood. Although its function is not fully understood, serum amyloid A1 appears to play a role in the immune system. SAA1 is closely associated with high-density lipoprotein. Additionally, SAA1 interacts with a number of mammalian proteins. These receptors include the G protein-coupled chemoattractant receptor FPR2. Certain studies indicated that SAA1 might contribute to the development of atherosclerosis. SAA1 is also presented in macrophages and epithelial cells in various tissues. It has been found to enhance local Th17 response in the gut. Other studies have shown that native human SAA1 retains some of the cytokine-like activities such as the G-CSF-induction capability. In a case, the findings suggested that a mutation in the SAA1 promoter causes hereditary amyloid A amyloidosis. Besides, as SAA1 transcriptionally activated by STAT3, it could accelerate renal interstitial fibrosis by inducing endoplasmic reticulum stress; SAA1knockdown promotes the apoptosis of glioblastoma cells via downregulation of AKT signaling.

  • Datasheet & COA:
    Please contact us to get it.

產品評價

問答及客戶評論

 常見問題解答
Q:

CSB-EP020656BO 客戶問為什么MW是33 kDa,很多文獻上寫的是12kDa

A:
CSB-EP020656BO N-terminal 6xHis-SUMO-tagged and C-terminal Myc-tagged, CSB-EP020656BOb3 N-terminal 10xHis-SUMO-tagged and C-terminal Myc-taggedd, CSB-EP020656BOa0 N-terminal 6xHis-tagged, 我們的分子量大小是包含標簽的分子量大小的,您在文獻中看到的12kd,指的應該是19-130aa,無標簽對應的僅目的蛋白的分子量大小,若您想要小標簽的話,優先推薦CSB-EP020656BOa0 N-terminal 6xHis-tagged。

靶點詳情

  • 功能:
    Major acute phase reactant. Apolipoprotein of the HDL complex.
  • 基因功能參考文獻:
    1. polymorphisms in the SAA2 gene are associated with milk production traits in Chinese Holstein cows PMID: 26373797
  • 相關疾?。?/div>
    Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    SAA family
  • 組織特異性:
    Expressed by the liver; secreted in plasma.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲色大成网站www永久| 小草国产精品情侣| 亚洲日韩中文字幕在线播放| 中文字幕无码av波多野吉衣| 精品久久久久久无码国产| 国精品午夜福利视频| 亚洲综合久久一本伊一区| 欧美成人片在线观看| 国产精品无码永久免费不卡| 亚洲综合区小说区激情区| 2020精品国产户外| 狠狠色综合tv久久久久久| 人妻在客厅被c的呻吟| 国模无码一区二区三区不卡| 成人午夜精品无码一区二区三区| 欧美牲交a欧牲交aⅴ久久| 国产成人a人亚洲精品无码| 久久69精品久久久久久hb| 久久精品国产日本波多野结衣 | 丁香婷婷综合激情五月色| 中文字幕色av一区二区三区| 亚洲国产成人极品综合| 亚洲精品无码伊人久久| 国产乱xxⅹxx国语对白| 久久久久久a亚洲欧洲av| 日本在线a一区视频| 亚洲色素色无码专区| 老鲁夜夜老鲁| 成人亚洲欧美在线观看| 欧美亚洲日本日韩在线| 欧美饥渴熟妇高潮喷水水| 精品国内自产拍在线观看视频| 玩肥熟老妇bbw视频| 综合图区亚洲欧美另类图片| 丰满人妻熟妇乱又伦精品视| 亚洲国产成人久久综合电影| 国产成人精品a视频免费福利| 真人作爱免费视频| 99久久国产自偷自偷免费一区| 中文字幕人妻被公上司喝醉506| 婷婷成人综合激情在线视频播放 |