在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Bovine NACHT, LRR and PYD domains-containing protein 3 (NLRP3), partial

Recombinant Bovine NACHT, LRR and PYD domains-containing protein 3 (NLRP3), partial

  • 中文名稱：
    牛NLRP3重組蛋白
  • 貨號：
    CSB-YP015871BO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛NLRP3重組蛋白
  • 貨號：
    CSB-EP015871BO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛NLRP3重組蛋白
  • 貨號：
    CSB-EP015871BO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛NLRP3重組蛋白
  • 貨號：
    CSB-BP015871BO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛NLRP3重組蛋白
  • 貨號：
    CSB-MP015871BO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    NLRP3; NACHT; LRR and PYD domains-containing protein 3
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    As the sensor component of the NLRP3 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, initiates the formation of the inflammasome polymeric complex, made of NLRP3, PYCARD and CASP1 (or possibly CASP4/CASP11). Recruitment of proCASP1 to the inflammasome promotes its activation and CASP1-catalyzed IL1B and IL18 maturation and secretion in the extracellular milieu. Activation of NLRP3 inflammasome is also required for HMGB1 secretion. The active cytokines and HMGB1 stimulate inflammatory responses. Inflammasomes can also induce pyroptosis, an inflammatory form of programmed cell death. Under resting conditions, NLRP3 is autoinhibited. NLRP3 activation stimuli include extracellular ATP, reactive oxygen species, K(+) efflux, crystals of monosodium urate or cholesterol, amyloid-beta fibers, environmental or industrial particles and nanoparticles, cytosolic dsRNA, etc. However, it is unclear what constitutes the direct NLRP3 activator. Activation in presence of cytosolic dsRNA is mediated by DHX33. Independently of inflammasome activation, regulates the differentiation of T helper 2 (Th2) cells and has a role in Th2 cell-dependent asthma and tumor growth. During Th2 differentiation, required for optimal IRF4 binding to IL4 promoter and for IRF4-dependent IL4 transcription. Binds to the consensus DNA sequence 5'-GRRGGNRGAG-3'. May also participate in the transcription of IL5, IL13, GATA3, CCR3, CCR4 and MAF.
  • 亞細胞定位：
    Cytoplasm, cytosol. Inflammasome. Endoplasmic reticulum. Secreted. Nucleus.
  • 蛋白家族：
    NLRP family
  • 數據庫鏈接：


主站蜘蛛池模板： 草草影院发布页| 人妻无码中字在线a| 无码超乳爆乳中文字幕| 中文成人在线| 免费国产a国产片高清网站| 无码av岛国片在线播放| 人妻熟妇乱又伦精品视频无广告| 伴郎粗大的内捧猛烈进出视频观看 | 一区二区三区在线 | 欧洲| 欧美人与物videos另类xxxxx | 国产在线精品一区二区中文| 日本不卡高字幕在线2019| 亚洲国产一区二区三区在观看| 中老年熟妇激情啪啪大屁股| 人人爽人人添人人超| 国产日产久久高清欧美一区| 国产精品情侣呻吟对白视频| 尤物av无码国产在线看| 综合色一色综合久久网| 人人妻人人澡人人爽人人精品电影| 欧美私人情侣网站| 亚洲精品国产自在现线看| 超清中文乱码一区| 精品人妻伦九区久久aaa片| 久久久久青草线综合超碰| 18禁止午夜福利体验区| 一本一道av无码中文字幕﹣百度| 爱性久久久久久久久| 欧美人成视频在线视频| 亚洲bbw性色大片| 色多多性虎精品无码av| 2020最新国产在线不卡a| 玩弄放荡人妻少妇系列| 69sex久久精品国产麻豆| 久久/这里只精品热在线获取| 热の综合热の国产热の潮在线| 4444亚洲人成无码网在线观看 | 人妻va精品va欧美va| 无码少妇a片一区二区三区| 欧美综合自拍亚洲图久青草| 野外做受又硬又粗又大视频√|