在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Bovine NACHT, LRR and PYD domains-containing protein 3 (NLRP3), partial

Recombinant Bovine NACHT, LRR and PYD domains-containing protein 3 (NLRP3), partial

  • 中文名稱：
    牛NLRP3重組蛋白
  • 貨號：
    CSB-YP015871BO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛NLRP3重組蛋白
  • 貨號：
    CSB-EP015871BO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛NLRP3重組蛋白
  • 貨號：
    CSB-EP015871BO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛NLRP3重組蛋白
  • 貨號：
    CSB-BP015871BO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛NLRP3重組蛋白
  • 貨號：
    CSB-MP015871BO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    NLRP3; NACHT; LRR and PYD domains-containing protein 3
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    As the sensor component of the NLRP3 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, initiates the formation of the inflammasome polymeric complex, made of NLRP3, PYCARD and CASP1 (or possibly CASP4/CASP11). Recruitment of proCASP1 to the inflammasome promotes its activation and CASP1-catalyzed IL1B and IL18 maturation and secretion in the extracellular milieu. Activation of NLRP3 inflammasome is also required for HMGB1 secretion. The active cytokines and HMGB1 stimulate inflammatory responses. Inflammasomes can also induce pyroptosis, an inflammatory form of programmed cell death. Under resting conditions, NLRP3 is autoinhibited. NLRP3 activation stimuli include extracellular ATP, reactive oxygen species, K(+) efflux, crystals of monosodium urate or cholesterol, amyloid-beta fibers, environmental or industrial particles and nanoparticles, cytosolic dsRNA, etc. However, it is unclear what constitutes the direct NLRP3 activator. Activation in presence of cytosolic dsRNA is mediated by DHX33. Independently of inflammasome activation, regulates the differentiation of T helper 2 (Th2) cells and has a role in Th2 cell-dependent asthma and tumor growth. During Th2 differentiation, required for optimal IRF4 binding to IL4 promoter and for IRF4-dependent IL4 transcription. Binds to the consensus DNA sequence 5'-GRRGGNRGAG-3'. May also participate in the transcription of IL5, IL13, GATA3, CCR3, CCR4 and MAF.
  • 亞細胞定位：
    Cytoplasm, cytosol. Inflammasome. Endoplasmic reticulum. Secreted. Nucleus.
  • 蛋白家族：
    NLRP family
  • 數據庫鏈接：


主站蜘蛛池模板： 爆乳高潮喷水无码正在播放| 中文字幕av高清片| 天天爽夜夜爽人人爽从早干到睌| 免费无码又爽又刺激成人| 五月天精品视频在线观看| 中文字幕丰满乱子伦无码专区| 人妻丰满熟妇无码区免费| 天堂8а√中文在线官网| 亚洲乱码在线卡一卡二卡新区| 欧美成人午夜精品久久久| 亚洲欧美日韩中文无线码| 国产原创av中文在线观看| 好疼太大了太粗太长了视频| 成 年 人 黄 色 大 片大 全| 亚洲精品专区在线观看| 麻豆人妻无码性色av专区| 无码人妻精品一区二区三区蜜桃| 国产国语亲子伦亲子| 日本三级成本人网站| av无码人妻无码男人的天堂| 日本肉体裸xxxxbbbb| 国语自产少妇精品视频| 国产av人人夜夜澡人人爽 | 亚洲综合精品成人| 亚洲美女被黑人巨大在线播放| 激情五月综合色婷婷一区二区 | 综合久久久久6亚洲综合| 137肉体摄影日本裸交| 免费99精品国产自在在线| 日韩精品无码一本二本三本色| 内谢少妇xxxxx8老少交| 精品久久久无码中文字幕 | 成人亚洲一区无码久久| 欧美大片aaaaa免费观看| 久久精品国产99久久久古代| 永久黄网站色视频免费无下载| 野花社区免费观看在线www| 伦伦影院午夜理论片| 在线亚洲欧美日韩精品专区| 大香伊蕉在人线国产最新75| 丁香婷婷综合激情五月色|