在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine N-myc-interactor (NMI)

  • 中文名稱:
    牛NMI重組蛋白
  • 貨號:
    CSB-YP673620BO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    牛NMI重組蛋白
  • 貨號:
    CSB-EP673620BO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    牛NMI重組蛋白
  • 貨號:
    CSB-EP673620BO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    牛NMI重組蛋白
  • 貨號:
    CSB-BP673620BO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    牛NMI重組蛋白
  • 貨號:
    CSB-MP673620BO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    NMI; N-myc-interactor; Nmi; N-myc and STAT interactor
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-309
  • 氨基酸序列
    MSADEDNKEQ VLKECEQAEE IMKDKQNQKL ISEITKENIQ LKEEIKKLEA ELQETTRTSQ INEDIPETKI KFTSVENPES DSEFSDISYS CQVSSKVPYE LQKGQALITF EKEEVAQNVI RMEYHHVQVQ NENVMLTANP VSLNSGVKFQ VHVGVSKMKI NVTDIPDELP ESQMRDKLEL SFSKSRNGGG EVEYVEYNKQ TRSALITFVE SGVADKILKM KDYPLYINQN CHRVTVYPYT ETHLKKFQVF SGVSKRTVLL TGLKHLQTTD EEVVEDFISI HFQREKNGGG EVEVVKCSLG QPHTAYFEE
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as a signaling pathway regulator involved in innate immune system response. In response to interleukin 2/IL2 and interferon IFN-gamma/IFNG, interacts with signal transducer and activator of transcription/STAT which activate the transcription of downstream genes involved in a multitude of signals for development and homeostasis. Enhances the recruitment of CBP/p300 coactivators to STAT1 and STAT5, resulting in increased STAT1- and STAT5-dependent transcription. In response to interferon IFN-alpha, associates in a complex with signaling pathway regulator IFI35 to regulate immune response; the complex formation prevents proteasome-mediated degradation of IFI35. In complex with IFI35, inhibits virus-triggered type I IFN-beta production when ubiquitinated by ubiquitin-protein ligase TRIM21. In complex with IFI35, negatively regulates nuclear factor NF-kappa-B signaling by inhibiting the nuclear translocation, activation and transcription of NF-kappa-B subunit p65/RELA, resulting in the inhibition of endothelial cell proliferation, migration and re-endothelialization of injured arteries. Negatively regulates virus-triggered type I interferon/IFN production by inducing proteosome-dependent degradation of IRF7, a transcriptional regulator of type I IFN, thereby interfering with cellular antiviral responses. Beside its role as an intracellular signaling pathway regulator, also functions extracellularly as damage-associated molecular patterns (DAMPs) to promote inflammation, when actively released by macrophage to the extracellular space during cell injury or pathogen invasion. Macrophage-secreted NMI activates NF-kappa-B signaling in adjacent macrophages through Toll-like receptor 4/TLR4 binding and activation, thereby inducing NF-kappa-B translocation from the cytoplasm into the nucleus which promotes the release of proinflammatory cytokines.
  • 亞細胞定位:
    Cytoplasm. Nucleus. Secreted.
  • 蛋白家族:
    NMI family
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲性人人天天夜夜摸18禁止 | 99精品久久久久中文字幕| 人妻少妇88久久中文字幕| 色综合久久网| 久久精品亚洲日本波多野结衣| 色噜噜狠狼综合在线| 亚洲精品一区二区国产精华液| 国模杨依粉嫩蝴蝶150p| 久9re热视频这里只有精品| 久久亚洲美女精品国产精品 | 青青久久成人免费影院| 精品无码国产一区二区三区av| 欧美又大粗又爽又黄大片视频 | 亚洲中文字幕aⅴ无码天堂| 亚洲欧洲综合有码无码| 狠狠躁18三区二区一区| 四虎国产成人永久精品免费| 久久亚洲中文字幕精品一区| 大伊香蕉精品一区二区| 国产福利视频在线观看| 日本精品一区二区三区四区| 日韩精品国产另类专区| 免费的污污的网站在线观看| 亚洲精品色在线网站| 天天躁日日躁狠狠躁2018| 亚洲熟妇无码八v在线播放| 久久亚洲精品无码va白人极品| 级毛片内射视频| 美女黄频视频大全免费的国内| 免费很黄无遮挡的视频| 女人高潮被爽到呻吟在线观看| 亚洲成年网站青青草原| www一区二区乱码www| 免费精品99久久国产综合精品| 无码人妻一区二区三区一| 久久婷婷狠狠综合激情| 国产又黄又爽又色的免费视频 | 55夜色66夜色国产精品视频| 亚洲男人最新版本天堂| 俺也来俺也去俺也射| 色天使亚洲综合一区二区|