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  4. Recombinant Bovine Myocyte-specific enhancer factor 2A (MEF2A)

Recombinant Bovine Myocyte-specific enhancer factor 2A (MEF2A)

  • 中文名稱：
    牛MEF2A重組蛋白
  • 貨號：
    CSB-YP013670BO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛MEF2A重組蛋白
  • 貨號：
    CSB-EP013670BO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛MEF2A重組蛋白
  • 貨號：
    CSB-EP013670BO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛MEF2A重組蛋白
  • 貨號：
    CSB-BP013670BO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛MEF2A重組蛋白
  • 貨號：
    CSB-MP013670BO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    MEF2AMyocyte-specific enhancer factor 2A
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-492
  • 氨基酸序列
    MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS SNKLFQYAST DMDKVLLKYT EYNEPHESRT NSDIVEALNK KEHRGCDSPD PDTSYVLTPH TEEKYKKINE EFDNMMRNHK IAPGLPPQNF SMSVTVPVTS PSALSYTNPG SSLVSPSLAA SSALADTSML SPPQATLHRN VSPGAPQRPP STGSAGGMLS TSDLTVPNGA GSSPVGNGFV NSRASPNLIG TTGANSLGKV MPTKSPPPPG GGSLGMNSRK PDLRVVIPPS SKGMMPPLNT QRISSSQATQ PLATPVVSVT TPSLPPQGLV YSAMPTAYNT DYSLTSADLS ALQGFNSPGM LSLGQVSAWQ QHHLGQAALN SLVAGGQLSQ GSNLSINTNQ NINIKSEPIS PPRDRMTPSG FQQQQQPQPP PPPPQAPQPQ PRQEVGRSPV DSLSSSSSSY DGSDREDPRG DFHSPVVLGR PPNSEDRESP SVKRMRMDAW VT
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
  • 基因功能參考文獻：
    1. MEF2A is a positive regulator in skeletal muscle myoblast proliferation PMID: 29698438
    2. polymorphisms in the bovine MEF2A gene and their effect on the MEF2A mRNA expression level in the longissimus dorsi muscle PMID: 22320864
  • 亞細胞定位：
    Nucleus.
  • 數據庫鏈接：


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