在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Mu-type opioid receptor (OPRM1), partial

  • 中文名稱:
    牛OPRM1重組蛋白
  • 貨號:
    CSB-YP016361BO1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    牛OPRM1重組蛋白
  • 貨號:
    CSB-EP016361BO1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    牛OPRM1重組蛋白
  • 貨號:
    CSB-EP016361BO1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    牛OPRM1重組蛋白
  • 貨號:
    CSB-BP016361BO1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    牛OPRM1重組蛋白
  • 貨號:
    CSB-MP016361BO1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    OPRM1; Mu-type opioid receptor; M-OR-1; MOR-1
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell type-specific activity is predominantly coupled to pertussis toxin-sensitive G(i) and G(o) G alpha proteins, GNAI1, GNAI2, GNAI3 and GNAO1, and to a lesser extent to pertussis toxin-insensitive G alpha proteins GNAZ and GNA15. They mediate an array of downstream cellular responses, including inhibition of adenylate cyclase activity and both N-type and L-type calcium channels, activation of inward rectifying potassium channels, mitogen-activated protein kinase (MAPK), phospholipase C (PLC), phosphoinositide/protein kinase (PKC), phosphoinositide 3-kinase (PI3K) and regulation of NF-kappa-B. Also couples to adenylate cyclase stimulatory G alpha proteins. The selective temporal coupling to G-proteins and subsequent signaling can be regulated by RGSZ proteins, such as RGS9, RGS17 and RGS4. Phosphorylation by members of the GPRK subfamily of Ser/Thr protein kinases and association with beta-arrestins is involved in short-term receptor desensitization. Beta-arrestins associate with the GPRK-phosphorylated receptor and uncouple it from the G-protein thus terminating signal transduction. The phosphorylated receptor is internalized through endocytosis via clathrin-coated pits which involves beta-arrestins. The activation of the ERK pathway occurs either in a G-protein-dependent or a beta-arrestin-dependent manner and is regulated by agonist-specific receptor phosphorylation. Acts as a class A G-protein coupled receptor (GPCR) which dissociates from beta-arrestin at or near the plasma membrane and undergoes rapid recycling. Receptor down-regulation pathways are varying with the agonist and occur dependent or independent of G-protein coupling. Endogenous ligands induce rapid desensitization, endocytosis and recycling. Heterooligomerization with other GPCRs can modulate agonist binding, signaling and trafficking properties. Involved in neurogenesis.
  • 基因功能參考文獻:
    1. analysis of solubilization of mu-opioid receptors enriched from bovine brain membranes PMID: 22896890
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cell projection, axon. Perikaryon. Cell projection, dendrite. Endosome.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數據庫鏈接:

    KEGG: bta:281958

    STRING: 9913.ENSBTAP00000026280

    UniGene: Bt.242



主站蜘蛛池模板: 狠狠色噜噜狠狠狠狠五月婷| 在线播放人成视频观看| 日产精品卡2卡三卡乱码网站| av中文字幕无码免费看| 99精品久久精品一区二区| 精品熟人妻一区二区三区四区不卡| 亚洲伊人久久综合成人| 日日摸日日碰夜夜爽无| 中国极品少妇videossexhd| 久久伊人色av天堂九九| 大学生被内谢粉嫩无套| 欧美人与动牲交免费观看网| 99精品众筹模特自拍视频| 国产福利视频在线观看| 日本在线观看| 日本免码va在线看免费| 日韩人妻无码一区二区三区俄罗斯 | 亚洲 熟女 久久 国产| 国模小黎自慰gogo人体| 国内精品伊人久久久久av| 久久无码超清激情av| 国产精品白丝av网站在线观看| 欧美老妇大p毛茸茸| 国产男生午夜福利免费网站| 变态另类先锋影音| 欧美人伦禁忌dvd放荡欲情| 草草影院发布页| 午夜福利理论片高清在线| 久久99亚洲精品久久69| 国产98在线 | 免费、| 99蜜桃在线观看免费视频网站| 狠狠色狠狠色五月激情| 国产网红女主播精品视频| 丰满人妻熟妇乱又伦精品视| 骚女人干起来舒服视频在线| 免费网站内射红桃视频| wwww亚洲熟妇久久久久| 中文在线а天堂| 国产精品亚洲二区在线看| 精品1卡二卡三卡四卡老狼| 欧美精品乱码99久久蜜桃|