在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Mu-type opioid receptor (OPRM1), partial

  • 中文名稱:
    牛OPRM1重組蛋白
  • 貨號:
    CSB-YP016361BO1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    牛OPRM1重組蛋白
  • 貨號:
    CSB-EP016361BO1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    牛OPRM1重組蛋白
  • 貨號:
    CSB-EP016361BO1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    牛OPRM1重組蛋白
  • 貨號:
    CSB-BP016361BO1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    牛OPRM1重組蛋白
  • 貨號:
    CSB-MP016361BO1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    OPRM1; Mu-type opioid receptor; M-OR-1; MOR-1
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell type-specific activity is predominantly coupled to pertussis toxin-sensitive G(i) and G(o) G alpha proteins, GNAI1, GNAI2, GNAI3 and GNAO1, and to a lesser extent to pertussis toxin-insensitive G alpha proteins GNAZ and GNA15. They mediate an array of downstream cellular responses, including inhibition of adenylate cyclase activity and both N-type and L-type calcium channels, activation of inward rectifying potassium channels, mitogen-activated protein kinase (MAPK), phospholipase C (PLC), phosphoinositide/protein kinase (PKC), phosphoinositide 3-kinase (PI3K) and regulation of NF-kappa-B. Also couples to adenylate cyclase stimulatory G alpha proteins. The selective temporal coupling to G-proteins and subsequent signaling can be regulated by RGSZ proteins, such as RGS9, RGS17 and RGS4. Phosphorylation by members of the GPRK subfamily of Ser/Thr protein kinases and association with beta-arrestins is involved in short-term receptor desensitization. Beta-arrestins associate with the GPRK-phosphorylated receptor and uncouple it from the G-protein thus terminating signal transduction. The phosphorylated receptor is internalized through endocytosis via clathrin-coated pits which involves beta-arrestins. The activation of the ERK pathway occurs either in a G-protein-dependent or a beta-arrestin-dependent manner and is regulated by agonist-specific receptor phosphorylation. Acts as a class A G-protein coupled receptor (GPCR) which dissociates from beta-arrestin at or near the plasma membrane and undergoes rapid recycling. Receptor down-regulation pathways are varying with the agonist and occur dependent or independent of G-protein coupling. Endogenous ligands induce rapid desensitization, endocytosis and recycling. Heterooligomerization with other GPCRs can modulate agonist binding, signaling and trafficking properties. Involved in neurogenesis.
  • 基因功能參考文獻:
    1. analysis of solubilization of mu-opioid receptors enriched from bovine brain membranes PMID: 22896890
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cell projection, axon. Perikaryon. Cell projection, dendrite. Endosome.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數據庫鏈接:

    KEGG: bta:281958

    STRING: 9913.ENSBTAP00000026280

    UniGene: Bt.242



主站蜘蛛池模板: 在线观看成人无码中文av天堂不卡 | 人妻aⅴ无码一区二区三区| 国产精品欧美亚洲韩国日本久久| 国产精品久久久久久久久免费| 国产亚洲精品久久久ai换| 四虎影视无码永久免费| 国产色情又大又粗又黄的电影| 国产精品人人做人人爽| 欧美一区内射最近更新| 国产成人卡2卡3卡4乱码| 欧洲国产精品无码专区影院| 中文字幕人妻无码系列第三区| 性色av极品无码专区亚洲| 国产日产欧产精品精品ai| 777米奇色狠狠俺去啦| 激情人妻另类人妻伦| 久久精品中文騷妇女内射| 9999国产精品欧美久久久久久| 2020国产精品午夜福利在线观看 | 高清国产一区二区三区在线| 18禁黄网站禁片免费观看女女 | 玩弄人妻少妇老师美妇厨房| 亚洲综合另类小说色区一| 国产乡下三级全黄三级bd| 亚洲国产欧美日韩精品一区二区三区| 人妻少妇熟女javhd| 欧美成人在线视频| 欧美成人精品三级一二三在线观看 | 国产最新av在线播放不卡| 一边吃奶一边做动态图| 国产老熟女网站| 日韩精品真人荷官无码| √天堂中文最新版在线中文| 天天摸天天碰天天添| 亚洲系列一区中文字幕| 在线看午夜福利片国产| 久久www免费人成一看片| 亚洲不乱码卡一卡二卡4卡5| 国产av国片精品一区二区| 制服丝袜中文字幕在线| 人妻激情偷乱一区二区三区|