Recombinant Bovine Metalloproteinase inhibitor 3 (TIMP3)

中文名稱：

牛TIMP3重組蛋白
貨號：

CSB-YP023562BO
規格：
來源：

Yeast
其他：

中文名稱：

牛TIMP3重組蛋白
貨號：

CSB-EP023562BO
規格：
來源：

E.coli
其他：

中文名稱：

牛TIMP3重組蛋白
貨號：

CSB-EP023562BO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

牛TIMP3重組蛋白
貨號：

CSB-BP023562BO
規格：
來源：

Baculovirus
其他：

中文名稱：

牛TIMP3重組蛋白
貨號：

CSB-MP023562BO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

TIMP3
Uniprot No.：

P79121
別名：

TIMP3; Metalloproteinase inhibitor 3; Tissue inhibitor of metalloproteinases 3; TIMP-3
種屬：

Bos taurus (Bovine)
蛋白長度：

Full Length of Mature Protein
表達區域：

24-211
氨基酸序列

CTCSPSHPQDAFCNSDIVIRAKVVGKKLLKEGPFGTMVYTIKQMKMYRGFTKMPHVQYIH TEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNFVERWDQLTLSQRKGLNYRYHLGC NCKIKSCYYLPCFVTSKNECLWTDMFSNFGYPGYQSKHYACIRQKGGYCSWYRGWAPPDK SIINATDP
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli.
基因功能參考文獻：
1. Reactive oxygen species mediate TGF-beta1-induced TIMP-3 gene expression PMID: 15203191
2. TIMP3 has a role in the pericyte-induced stabilization of newly formed vascular networks that are predisposed to undergo regression and reveal specific molecular targets of the inhibitors regulating these events. PMID: 17030988
3. TIMP3 mRNA expression level was upregulated by multidirectional articular motion. PMID: 17518631
亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

Protease inhibitor I35 (TIMP) family
數據庫鏈接：

KEGG: bta:282094

STRING: 9913.ENSBTAP00000027504

UniGene: Bt.10882