在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Krev interaction trapped protein 1 (KRIT1), partial

  • 中文名稱:
    牛KRIT1重組蛋白
  • 貨號:
    CSB-YP754378BO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    牛KRIT1重組蛋白
  • 貨號:
    CSB-EP754378BO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    牛KRIT1重組蛋白
  • 貨號:
    CSB-EP754378BO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    牛KRIT1重組蛋白
  • 貨號:
    CSB-BP754378BO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    牛KRIT1重組蛋白
  • 貨號:
    CSB-MP754378BO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    KRIT1; CCM1Krev interaction trapped protein 1; Krev interaction trapped 1; Cerebral cavernous malformations 1 protein homolog
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner.
  • 基因功能參考文獻:
    1. Rap1 increases KRIT-1 targeting to endothelial cell-cell junctions where it suppresses stress fibers and stabilizes junctional integrity. PMID: 17954608
  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell junction.
  • 數據庫鏈接:


主站蜘蛛池模板: 夜夜夜夜猛噜噜噜噜噜| 亚洲精品久久yy5099| 日日大香人伊一本线久| 亚洲线精品一区二区三区| 午夜无码人妻av大片色欲| 精品无码一区二区三区在线| 亚洲天堂2017无码| 男女下面一进一出好爽视频| 男女啪啪网站大全免费| 精品国偷自产在线| 99久久国语露脸精品国产| 国产免费又色又爽又黄软件| 亚洲а∨天堂男人色无码| 少妇无码av无码专区在线观看| 中文字幕一区二区人妻电影| 亚洲春色av无码专区在线播放| 国产熟睡乱子伦午夜视频麻豆| 美女网站免费观看视频| 大香伊蕉在人线国产网站首页| 先锋影音人妻啪啪va资源网站| 蜜臀av性久久久久蜜臀aⅴ麻豆| 无码中文字幕色专区| 丁香五月婷激情综合第九色| 久久天天躁夜夜躁狠狠躁| 精品亚洲成a人在线观看| 免费大黄网站| 成视频年人黄网站视频福利| 成码无人av片在线电影网站| 国产老熟女伦老熟妇露脸| 色偷偷av一区二区三区| 亚洲kkk4444在线观看| 国产一区二区三区在线观看免费 | 日日噜噜噜夜夜爽爽狠狠| 狠狠色噜噜狠狠狠狠888奇禾| av无码午夜福利一区二区三区| 综合久久给合久久狠狠狠97色| 日韩精品a片一区二区三区妖精| a 'v片欧美日韩在线| 亚洲色大成影网站www永久| 国产精品美女被遭强扒开双腿| 欧美成人综合久久精品|