在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Caspase-4 (CASP4), partial

  • 中文名稱:
    Recombinant Bovine Caspase-4(CASP4) ,partial
  • 貨號:
    CSB-YP691616BO
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Bovine Caspase-4(CASP4) ,partial
  • 貨號:
    CSB-EP691616BO
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Bovine Caspase-4(CASP4) ,partial
  • 貨號:
    CSB-EP691616BO-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Bovine Caspase-4(CASP4) ,partial
  • 貨號:
    CSB-BP691616BO
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Bovine Caspase-4(CASP4) ,partial
  • 貨號:
    CSB-MP691616BO
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    CASP4Caspase-4; CASP-4; EC 3.4.22.57) [Cleaved into: Caspase-4 subunit 1; Caspase-4 subunit 2]
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    Partial
  • 表達(dá)區(qū)域:
    -
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Inflammatory caspase that acts as an essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non-canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Thiol protease that cleaves a tetrapeptide after an Asp residue at position P1. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, followed by IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators. Plays a crucial role in the restriction of Salmonella typhimurium replication in colonic epithelial cells during infection: in later stages of the infection, LPS from cytosolic Salmonella triggers CASP4 activation, which catalyzes cleavage of GSDMD, resulting in pyroptosis of infected cells and their extrusion into the gut lumen, as well as in IL18 secretion. Cleavage of GSDMD is not strictly dependent on the consensus cleavage site but depends on an exosite interface on CASP4 that recognizes and binds the Gasdermin-D, C-terminal (GSDMD-CT) part. Pyroptosis limits bacterial replication, while cytokine secretion promotes the recruitment and activation of immune cells and triggers mucosal inflammation. Involved in LPS-induced IL6 secretion; this activity may not require caspase enzymatic activity. Involved in cell death induced by endoplasmic reticulum stress. Activated by direct binding to LPS without the need of an upstream sensor. Does not directly process IL1B. During non-canonical inflammasome activation, cuts CGAS and may play a role in the regulation of antiviral innate immune activation.
  • 亞細(xì)胞定位:
    Cytoplasm, cytosol. Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion. Inflammasome. Secreted.
  • 蛋白家族:
    Peptidase C14A family
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 疯狂做受xxxx高潮欧美日本| 大肉大捧一进一出好爽视频mba | 国产精品亚洲综合一区二区三区 | 亚洲免费观看在线视频| 欧美精品久久久久久久自慰| 风韵饥渴少妇在线观看| 欧美人与动zozo在线播放| 免费无码黄十八禁网站在线观看| 国产日韩在线视看第一页| 久久精品中文字幕无码| 国模无码人体一区二区| 国产一卡2卡3卡4卡国色天香| 麻豆果冻传媒2021精品传媒一区 | 久久精品手机观看| 国产精品成熟老女人| 国产性猛交╳xxx乱大交| 老司机性色福利精品视频| 亚洲人成网站在小说| 97se亚洲精品一区| 日韩av在线观看免费| 又爽又色禁片1000视频免费看| 久久久久人妻一区精品果冻| 免费看少妇作爱视频| 亚洲精品字幕| 欧美精品1卡二卡三卡四卡| 香蕉视频在线精品视频| 成在人线av无码免费| 久久久久国产精品人妻aⅴ天堂 | 国产免码va在线观看免费| 国产av一区最新精品| 日韩精品一区二区三区在线观看l| 热99re久久国超精品首页| 被黑人猛躁10次高潮视频| 久久电影网午夜鲁丝片免费| 亚洲精品卡2卡三卡4卡2卡乱码| 香草乱码一二三四区别| 久久国产一区二区三区| 亚洲熟女综合一区二区三区| 四十如虎的丰满熟妇啪啪| 亚洲va韩国va欧美va| 中文字幕亚洲乱码熟女在线|