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  4. Recombinant Bovine Appetite-regulating hormone (GHRL)

Recombinant Bovine Appetite-regulating hormone (GHRL)

  • 中文名稱：
    牛GHRL重組蛋白
  • 貨號：
    CSB-YP860197BO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛GHRL重組蛋白
  • 貨號：
    CSB-EP860197BO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛GHRL重組蛋白
  • 貨號：
    CSB-EP860197BO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛GHRL重組蛋白
  • 貨號：
    CSB-BP860197BO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛GHRL重組蛋白
  • 貨號：
    CSB-MP860197BO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    GHRLAppetite-regulating hormone; Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide) [Cleaved into: Ghrelin; Obestatin]
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Cytoplasmic domain
  • 表達區域：
    24-50
  • 氨基酸序列
    GSSFLSP EHQKLQRKEA KKPSGRLKPR
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.; Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
  • 基因功能參考文獻：
    1. GHRL is an important candidate gene that may be used to identify genetic variations that influence traits of economic importance in beef cattle PMID: 26782466
    2. It is involved both in the short-term regulation of feeding and in the long-term regulation of energy metabolisms which may affect growth and development of the neonate. PMID: 23910951
    3. Single nucleotide polymorphisms identified in the promoter region of the ghrelin gene could cause changes in the putative transcription factor binding sites. PMID: 22302398
    4. The effects of dietary energy on the metabolism of ghrelin, leptin and growth hormone secretagogue receptor in blood and tissues of steers are reported. PMID: 21724941
    5. The effect of single nucleotide polymorphisms in 6 genes and their associations with production factors in beef cattle are reported. PMID: 17785604
    6. ghrelin declined after glucose infusion and before the insulin peak; post-nadir surge in ghrelin may be regulated by the decline in circulating concentrations of glucose and nonesterified fatty acids PMID: 18292256

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Motilin family
  • 數據庫鏈接：


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