Recombinant Bovine Alpha-S2-casein (CSN1S2)

^{In Stock}

貨號：

CSB-EP355862BO
規格：

￥2328
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
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靶點詳情

產品詳情

純度：

Greater than 85% as determined by SDS-PAGE.
基因名：

CSN1S2
Uniprot No.：

P02663
別名：

Casocidin-1;Casocidin-I
種屬：

Bos taurus (Bovine)
蛋白長度：

Full Length of Mature Protein
來源：

E.coli
分子量：

39.7 kDa
表達區域：

16-222aa
氨基酸序列

KNTMEHVSSSEESIISQETYKQEKNMAINPSKENLCSTFCKEVVRNANEEEYSIGSSSEESAEVATEEVKITVDDKHYQKALNEINQFYQKFPQYLQYLYQGPIVLNPWDQVKRNAVPITPTLNREQLSTSEENSKKTVDMESTEVFTKKTKLTEEEKNRLNFLKKISQRYQKFALPQYLKTVYQHQKAMKPWIQPKTKVIPYVRYL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 6xHis-KSI-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Important role in the capacity of milk to transport calcium phosphate.; Casocidin-I inhibits the growth of E.coli and S.carnosus.
基因功能參考文獻：
1. Translation attenuation via 3' terminal codon usage in bovine mRNA is responsible for the difference in alpha-S2- and beta-casein profile in milk. PMID: 25826667
2. Data indicate that the pepsin-pancreatin digest of alphaS-Casein exhibited anxiolytic-like activity. PMID: 23580614
3. Alpha-S2-casein was less effective at preventing fibril formation by modified kappa-casein, whereas alpha- and alpha-S1 casein were comparably potent inhibitors. PMID: 21457703
4. Single strand conformation polymorphism (SSCP) is a particularly useful technique because it allows discrimination of alleles, including zebu-specific alleles at the CSN2 locus. PMID: 15747725
5. study reports the SNP and AA change that distinguishes the B allele from other alleles at the CSN1S2 locus PMID: 17582136
6. Substitution effects of paternal CSN2alpha(s1) allele versus CSN2alpha(s2) allele on protein yield deviations (YDs) are significant, whereas their effects on milk and fat YDs are not. PMID: 18263971
7. bovine milk alpha s2-casein readily forms fibrils in vitro. Upon incubation at neutral pH & 37 degrees C, spherical particles typical of alpha s2-casein rapidly converted to twisted, ribbon-like fibrils approximately 12 nm in diameter. PMID: 18302322
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亞細胞定位：

Secreted.
蛋白家族：

Alpha-casein family
組織特異性：

Mammary gland specific. Secreted in milk.
數據庫鏈接：

KEGG: bta:282209

STRING: 9913.ENSBTAP00000006590

UniGene: Bt.57616