在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Aggrecan core protein (ACAN), partial

  • 中文名稱:
    Recombinant Bovine Aggrecan core protein(ACAN) ,partial
  • 貨號:
    CSB-YP001130BO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Bovine Aggrecan core protein(ACAN) ,partial
  • 貨號:
    CSB-EP001130BO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Bovine Aggrecan core protein(ACAN) ,partial
  • 貨號:
    CSB-EP001130BO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Bovine Aggrecan core protein(ACAN) ,partial
  • 貨號:
    CSB-BP001130BO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Bovine Aggrecan core protein(ACAN) ,partial
  • 貨號:
    CSB-MP001130BO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    ACAN; AGC1Aggrecan core protein; Cartilage-specific proteoglycan core protein; CSPCP
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.
  • 基因功能參考文獻:
    1. the subsequent presentation of aggregan from ECM leads to CD4(+) T-cell activation and effector cell formation. PMID: 24032649
    2. Data show that expression of mRNAs for aggrecan, collagen type II, and versican were significantly effected by the intervention. PMID: 21289569
    3. The delayed activation of proMMPs and the relatively low cleavage efficiency of MMPs compared to ADAMTS5 (aggrecanase) explains the minor contribution of the MMP enzymes to aggrecan catabolism in vivo. PMID: 21055468
    4. Self-adhesion between highly negatively charged aggrecan macromolecules extracted from bovine cartilage extracellular matrix, was investigated. PMID: 21081100
    5. aggrecanase activity (a) is responsible for early TNFalpha-dependent aggrecan cleavage and GAG release in the meniscus and (b) might be involved in meniscal degeneration. PMID: 19778432
    6. Maintenance of structure and organization of extracellular matrix comprising chondron and pericellular microenvironment of chondrocytes in articular cartilage is important for distribution of newly synthesized aggrecan monomers within tissue. PMID: 12475642
    7. aggrecan plays a protective role in preventing degradation of collagen fibrils PMID: 12890681
    8. Changes in aggrecan and type II collagen promoter activity in transfected chondrocyte-laden cylindrical constructs were evaluated in response to a range of loading frequencies and durations. PMID: 16691412
    9. AGC1 mRNA expression level was upregulated by multidirectional articular motion. PMID: 17518631
    10. Homozygosity mapping in candidate regions in a small Dexter pedigree suggested aggrecan as the most likely candidate gene. Mutation screening revealed a 4-bp insertion in exon 11 (2266_2267insGGCA) and a second, rarer transition in exon 1 (-198C>T). PMID: 17952705
    11. identified multiple conserved amino acids within regions N- and C-terminal of aggrecan to the site of scission that may influence enzyme-substrate recognition, and may interact with exosites on ADAMTS-4 and ADAMTS-5 PMID: 19101611
    12. The objective of this study was to compare patterns of aggrecan processing by chondrocytes and meniscal fibrochondrocytes in tissue explants and cell-agarose constructs. PMID: 19260779

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Aggrecan/versican proteoglycan family
  • 數據庫鏈接:


主站蜘蛛池模板: 浓毛欧美老妇乱子伦视频| 亚洲欧洲自拍拍偷精品 美利坚| 国产午夜福利在线播放87| 天天综合色天天综合色hd| 成人小说亚洲一区二区三区| 少妇性l交大片| 国色精品卡一卡2卡3卡4卡在线| 欧美人与动人物姣配xxxx | 少妇的肉体aa片免费| 131美女爱做视频| 狠狠色综合久久丁香婷婷| 图片区小说区另类春色| 日本猛少妇色xxxxx猛叫| 亚洲国产精品成人一区二区在线| 制服 丝袜 亚洲 中文 综合| 亚洲欧美成人中文日韩电影网站| 国精产品999国精产品官网| 一本色综合网久久| 久久人妻国产精品| a毛片终身免费观看网站| 777久久精品一区二区三区无码| 高清国产亚洲精品自在久久| 大屁股国产白浆一二区| 熟女肥臀白浆大屁股一区二区| 亚洲男人的天堂在线播放| 国产精品福利视频一区| 亚洲国产精品久久久久4婷婷 | 国产免费无遮挡吸乳视频在线观看| 亚洲人色婷婷成人网站在线观看| 高潮毛片又色又爽免费| 国内精品久久久久影视老司机| 日韩欧美国产一区精品| 中文字幕美人妻亅u乚一596| 欧美私人情侣网站| 美女mm131午夜福利在线| 在线观看国产精品普通话对白精品| 亚洲熟妇av乱码在线观看| 影音先锋人妻av中文字幕久久| 无码熟熟妇丰满人妻porn| 中国内地毛片免费高清| 丰满爆乳在线播放|