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  4. Recombinant Bovine 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (PLCZ1), partial

Recombinant Bovine 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (PLCZ1), partial

  • 中文名稱：
    牛PLCZ1重組蛋白
  • 貨號：
    CSB-YP632268BO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    牛PLCZ1重組蛋白
  • 貨號：
    CSB-EP632268BO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    牛PLCZ1重組蛋白
  • 貨號：
    CSB-EP632268BO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛PLCZ1重組蛋白
  • 貨號：
    CSB-BP632268BO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛PLCZ1重組蛋白
  • 貨號：
    CSB-MP632268BO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    PLCZ1; PLCZ; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; EC 3.1.4.11; Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-1; PLC-zeta-1
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
  • 基因功能參考文獻：
    1. Data show that the level of actin/PLC-zeta interaction was twice as high in G-actin that reflected an increase in affinity. PMID: 28929980
    2. A novel splice variant of Phospholipase C zeta 1 in the testis tissues of adult and fetal Chinese Holstein bulls was characterized. PMID: 25501200
    3. Murine PLCZ1 and bovine PLCZ1 possess species-specific differences in activity and suggest potential differences in the mode of action of the protein between the two species PMID: 20357268
  • 亞細胞定位：
    Nucleus. Cytoplasm, perinuclear region.
  • 數據庫鏈接：


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