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  4. Recombinant Beta-catenin/armadillo-related protein 1 (bar-1), partial

Recombinant Beta-catenin/armadillo-related protein 1 (bar-1), partial

  • 中文名稱：
    Recombinant Beta-catenin/armadillo-related protein 1(bar-1) ,partial
  • 貨號：
    CSB-YP623232CXY
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Beta-catenin/armadillo-related protein 1(bar-1) ,partial
  • 貨號：
    CSB-EP623232CXY
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Beta-catenin/armadillo-related protein 1(bar-1) ,partial
  • 貨號：
    CSB-EP623232CXY-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Beta-catenin/armadillo-related protein 1(bar-1) ,partial
  • 貨號：
    CSB-BP623232CXY
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Beta-catenin/armadillo-related protein 1(bar-1) ,partial
  • 貨號：
    CSB-MP623232CXY
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    bar-1
  • Uniprot No.：
  • 別名：
    bar-1; pvl-1; spy-1; C54D1.6Beta-catenin/armadillo-related protein 1; Protruding vulva protein 1; Suppressor of polyray 1
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Participates in the Wnt signaling pathway which affects cell fate and may regulate the stem cell divisions of seam cells during larval development. Functions as a transcriptional activator but is dependent on the interaction with pop-1. Involved in maintaining lin-39 Hox expression and regulating glr-1 abundance at the synapses. Required for mab-5 expression during Q neuroblast migration and for oxidative stress-induced daf-16 signaling. Has roles in egg laying, vulva precursor cell fate determination, Q neuroblast migration, posterior ectodermal cell P12 specification, movement, body length, male tail development and dauer induction. Functionally redundant to wrm-1 and hmp-2.
  • 基因功能參考文獻：
    1. Neuroprotection from mutant huntingtin toxicity requires FOXO partner bar-1/Beta-catenin. PMID: 22956852
    2. promoter elements necessary for bar-1 expression in several cell types, including a 321-bp element sufficient for expression in ventral cord neurons and a 1.1-kb element sufficient for expression in the developing vulva and adult seam cells PMID: 15282167
    3. Caenorhabditis elegans, both WRM-1/beta-catenin and LIT-1 kinase localize to the anterior cell cortex during asymmetric cell division but to the nucleus of the posterior daughter afterward PMID: 16077003
    4. These results suggest that beta-catenin and APC may regulate asymmetric divisions or Wnt signaling. PMID: 17276345
    5. Membrane trafficking regulated by ipla-1 provides a mechanism to control the cortical asymmetry of beta-catenin. PMID: 18497747
    6. NHR-25 cooperates with the Wnt/beta-catenin asymmetry pathway to control differentiation of the T seam cell. PMID: 19654209

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  • 亞細胞定位：
    Cytoplasm. Nucleus. Membrane. Cell junction.
  • 蛋白家族：
    Beta-catenin family
  • 組織特異性：
    Expressed in body wall muscle cells, hypodermal seam cells, gonad sheath cells and vulval precursor cells.
  • 數據庫鏈接：

    KEGG: cel:CELE_C54D1.6

    STRING: 6239.C54D1.6

    UniGene: Cel.5480



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